Bioinformatics Lab @ Wilmer Institute, Johns Hopkins University

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HNF-1 has 285 co-regulatory transcription factors (TFs)

Summary Table (Download Table)

Co-regulatory TF Tissue -log(P)
COUP-TF/HNF-4 kidney 52.0041
HNF-1 kidney 51.5417
HNF-4ALPHA kidney 28.4158
GCNF kidney 28.1174
LHX3 small_intestine 25.0081
HNF-1 liver 24.3156
NKX6-2 small_intestine 24.2814
CRX kidney 23.6826
OCT-1 kidney 23.0364
E4BP4 liver 22.544
ALPHA-CP1 small_intestine 20.9774
CDP liver 20.9496
HNF-3ALPHA liver 20.905
NR2E3 kidney 20.1523
AFP1 colon 19.8666
MRF-2 colon 19.5377
CRX small_intestine 19.1628
TCF-4 kidney 18.8408
POU3F2 small_intestine 18.5937
HNF-4 kidney 18.3688
PBX1B liver 18.1811
PAX-6 kidney 17.5519
C/EBPGAMMA liver 17.5108
PPARG kidney 17.4318
C/EBPBETA liver 17.4039
CDP colon 17.3554
HNF-4 liver 17.1069
FREAC-3 kidney 16.9228
GCNF colon 16.8359
COUP-TF/HNF-4 liver 16.8303
TCF11/MAFG kidney 16.6728
NF-AT small_intestine 16.361
AP-2REP colon 16.0294
ERR_ALPHA kidney 15.9527
AREB6 kidney 15.9071
TCF-4 small_intestine 15.7544
ALX-4 liver 15.6534
GATA-X kidney 15.5567
SRY peripheral_nervous_system 15.4284
RORALPHA1 kidney 15.4257
MIF-1 small_intestine 14.9813
NKX6-1 kidney 14.707
WHN small_intestine 14.6889
HNF-1 small_intestine 14.5286
FREAC-3 liver 14.4652
HNF-1 colon 14.3057
GR liver 14.2095
HNF-4ALPHA liver 13.9526
ALX-4 small_intestine 13.8633
C/EBPALPHA liver 13.6637
PBX-1 colon 13.5046
HNF-6 liver 13.4557
NKX3A small_intestine 13.4023
PBX-1 liver 13.3331
HFH-3 small_intestine 13.1615
PBX1B colon 13.1267
CREB kidney 13.0753
NKX6-2 kidney 12.8775
HFH-3 liver 12.693
OCT-1 colon 12.6415
OCT-1 small_intestine 12.3422
XBP-1 kidney 12.2796
FOXJ2 blood 12.2792
ARP-1 liver 12.2363
CRX liver 12.23
PBX-1 kidney 11.9766
NF-KAPPAB_(P65) kidney 11.9412
HLF liver 11.894
TATA small_intestine 11.8121
NKX6-2 liver 11.6984
TATA kidney 11.6623
CRE-BP1/C-JUN kidney 11.6479
AR kidney 11.6387
FOXD3 liver 11.6256
NCX colon 11.6088
NF-KAPPAB kidney 11.5814
ARP-1 kidney 11.5673
PU.1 colon 11.5648
TBP small_intestine 11.5473
HFH-4 small_intestine 11.541
EF-C small_intestine 11.5283
IPF1 small_intestine 11.4176
COUP-TF/HNF-4 small_intestine 11.375
TEL-2 kidney 11.327
MEIS1B/HOXA9 small_intestine 11.2939
AP-1 colon 11.1132
GATA-1 heart 10.9916
AP-4 kidney 10.9828
CDP_CR3+HD colon 10.7745
TITF1 small_intestine 10.7717
FOXJ2 peripheral_nervous_system 10.7108
FOXJ2 colon 10.6824
FXR kidney 10.6536
MEF-2 colon 10.5765
C/EBPALPHA kidney 10.567
TATA liver 10.5542
SRF small_intestine 10.5223
FOXJ2 kidney 10.5203
USF bone_marrow 10.5183
GATA-1 kidney 10.4516
NKX6-1 colon 10.4401
TBP kidney 10.436
FREAC-7 kidney 10.404
FOXO4 small_intestine 10.3894
BACH2 colon 10.3621
EF-C kidney 10.3405
FREAC-3 small_intestine 10.3357
PBX1B kidney 10.2925
ATF4 kidney 10.2505
C-MYB peripheral_nervous_system 10.2346
FREAC-2 liver 10.2304
IRF1 colon 10.1854
FOXJ2 eye 10.1324
FAC1 peripheral_nervous_system 10.0647
TAL-1ALPHA/E47 kidney 10.0563
LBP-1 small_intestine 10.042
CART-1 small_intestine 10.0206
SMAD-4 kidney 9.99824
FOXO4 kidney 9.98919
MEF-2 small_intestine 9.93965
E4BP4 spleen 9.91275
LEF-1 liver 9.8713
TAX/CREB kidney 9.86223
AP-1 kidney 9.83536
TBP liver 9.83405
HNF-3ALPHA peripheral_nervous_system 9.83362
ETF ovary 9.75482
TAL-1BETA/E47 kidney 9.72782
TEF-1 prostate 9.65656
GATA-6 heart 9.60206
HFH-4 peripheral_nervous_system 9.55928
NF-1 kidney 9.53912
AP-2REP liver 9.47267
AMEF-2 peripheral_nervous_system 9.45789
HNF-6 peripheral_nervous_system 9.4445
AFP1 small_intestine 9.34691
STAT5B_(HOMODIMER) liver 9.33122
FOXO4 colon 9.30474
BACH1 colon 9.1648
FOXO3 small_intestine 9.16469
BRN-2 peripheral_nervous_system 9.10634
HEB colon 9.09371
PAX-3 kidney 9.01741
ATF kidney 8.98212
NR2E3 small_intestine 8.97156
SRY colon 8.95668
HAND1/E47 kidney 8.91599
NF-E2 kidney 8.8729
OCT-X colon 8.8559
SF-1 kidney 8.84709
CART-1 liver 8.77188
MEF-2 kidney 8.74905
HOXA4 liver 8.7386
SF-1 liver 8.72192
OCT-1 cervix 8.71849
SRF kidney 8.68023
NF-KAPPAB small_intestine 8.63668
YY1 peripheral_nervous_system 8.63267
CHX10 kidney 8.62597
CART-1 kidney 8.62524
LHX3 bone_marrow 8.60959
FOXJ2 liver 8.56844
BACH1 kidney 8.56435
PAX-2 kidney 8.5119
MEIS1A/HOXA9 liver 8.49913
FREAC-2 peripheral_nervous_system 8.48099
RSRFC4 kidney 8.45231
HEB kidney 8.44484
E47 peripheral_nervous_system 8.41997
ER liver 8.39776
AREB6 small_intestine 8.38324
ARP-1 colon 8.38264
NF-E2 colon 8.36342
C/EBPDELTA liver 8.32907
GATA-X small_intestine 8.30534
TFII-I colon 8.2853
AP-3 colon 8.24877
CRE-BP1 kidney 8.23878
FOXD3 small_intestine 8.23358
PBX-1 small_intestine 8.18719
RORALPHA2 liver 8.1863
PAX-8 kidney 8.15579
GCNF small_intestine 8.1216
OCT-1 bone 8.11372
CHX10 small_intestine 8.09357
TATA spleen 8.06925
PAX-2 colon 8.03489
C/EBPBETA spleen 7.98276
C-MYB colon 7.97382
STAT6 placenta 7.90031
ATF3 colon 7.86269
SRF heart 7.83853
NF-1 liver 7.83183
FOXO4 liver 7.83142
E4BP4 small_intestine 7.82351
RORALPHA1 liver 7.81267
CDP_CR1 liver 7.75917
POU3F2 prostate 7.71085
PITX2 heart 7.64104
RORALPHA2 kidney 7.59978
C/EBP liver 7.59628
NF-E2 small_intestine 7.58915
ATF3 kidney 7.55244
TCF-4 heart 7.5404
C/EBP colon 7.53507
USF ovary 7.531
E12 pancreas 7.52592
NF-Y peripheral_nervous_system 7.51974
GATA-4 kidney 7.48662
LBP-1 kidney 7.48434
FXR liver 7.45405
CDC5 bone 7.3675
SRY liver 7.29323
AREB6 colon 7.26293
C/EBPALPHA spleen 7.23965
GCNF peripheral_nervous_system 7.19435
STAT5A colon 7.16321
AP-4 colon 7.16234
NF-KAPPAB muscle 7.13521
CRX colon 7.09279
STAT5A prostate 7.09083
NRL kidney 7.07276
NKX3A liver 7.06594
GATA-6 liver 7.05604
PBX-1 pancreas 7.04256
STAT5A small_intestine 7.02308
EF-C liver 7.00281
HSF colon 6.96109
C/EBPBETA colon 6.96
HMG_IY liver 6.95276
HNF-6 small_intestine 6.95101
NRSF blood 6.94247
PPARG liver 6.94145
TITF1 colon 6.92002
SMAD-4 liver 6.9151
FREAC-7 skin 6.90668
LXR cervix 6.90144
GATA-4 small_intestine 6.89379
C-MYC/MAX cervix 6.85269
RORALPHA1 colon 6.83555
AHR/ARNT pancreas 6.83208
HNF-4ALPHA small_intestine 6.82829
ELF-1 colon 6.81461
PBX1B pancreas 6.80667
ARP-1 muscle 6.7977
STAT5A eye 6.76214
FREAC-7 liver 6.74929
BACH1 ovary 6.72954
FXR ovary 6.72474
TBP colon 6.71079
MEF-2 muscle 6.69966
STAT5B_(HOMODIMER) testis 6.69683
TFIIA liver 6.68448
AP-2ALPHA ovary 6.67629
CDP small_intestine 6.67268
IPF1 bone_marrow 6.64576
NRL ovary 6.63941
NF-Y kidney 6.63549
POU3F2 eye 6.62484
AP-2GAMMA ovary 6.60717
LBP-1 spleen 6.6063
ATF pancreas 6.59804
ALX-4 cervix 6.56089
MAZ small_intestine 6.5506
MEIS1B/HOXA9 liver 6.54654
GR kidney 6.45643
IRF1 liver 6.44464
C/EBP small_intestine 6.36209
NKX2-2 small_intestine 6.33833
STAT1 small_intestine 6.33387
OCT-X cervix 6.32141
CRX eye 6.27457
STAT6 larynx 6.27178
SRF skin 6.271
TEF prostate 6.26564
STAT6 small_intestine 6.26563
POU1F1 small_intestine 6.25831
STAT1 kidney 6.24402
NKX2-2 liver 6.23168
MZF1 kidney 6.21648
FREAC-7 lung 6.20302
GR spleen 6.19381
HNF-3ALPHA small_intestine 6.19154
CRE-BP1 small_intestine 6.17487
BACH1 stomach 6.16166

Distribution of Co-regulatory TFs

Description: this pie chart displays the distribution of co-regulatory transcription factors (TFs) in different tissues.

Color schema: the tissue with the largest percentage of co-regulatory TFs is colored dark red whereas the tissue with the smallest percentage of co-regulatory TFs is colored dark blue. Tissues with intermediate percentages of co-regulatory TFs are colored from light red to yellow and cyan and then to light blue.