Bioinformatics Lab @ Wilmer Institute, Johns Hopkins University

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PITX2 has 57 co-regulatory transcription factors (TFs)

Summary Table (Download Table)

Co-regulatory TF Tissue -log(P)
MEF-2 muscle 23.5485
CRX eye 19.1884
GATA-1 heart 16.97
LHX3 peripheral_nervous_system 13.6379
GATA-6 heart 12.7912
C/EBP muscle 11.6761
NKX6-1 heart 11.4494
STAT4 heart 11.0703
AP-1 heart 10.7507
NKX3A peripheral_nervous_system 10.4782
TGIF muscle 9.66399
MEIS1 heart 9.5493
PPARG skin 9.32037
FXR eye 8.9686
STAT5A eye 8.86426
MYOD eye 8.58718
GATA-X heart 8.55411
TCF11/MAFG heart 8.17463
TAL-1BETA/E47 eye 8.12741
POU3F2 peripheral_nervous_system 8.07753
TCF11 soft_tissue 8.01991
LHX3 kidney 7.9856
FOXJ2 kidney 7.9513
CART-1 peripheral_nervous_system 7.68463
HNF-1 heart 7.64104
FAC1 lymph_node 7.61051
FAC1 skin 7.55603
TAL-1BETA/ITF-2 muscle 7.55082
SRF muscle 7.54654
TAL-1ALPHA/E47 muscle 7.52894
CDP_CR3+HD muscle 7.52355
TEF muscle 7.40435
CACCC-BINDING_FACTOR ovary 7.30054
NF-Y eye 7.27981
RP58 muscle 7.26919
TCF11 peripheral_nervous_system 7.04263
C/EBP bone 6.97137
SRF heart 6.90899
GCNF muscle 6.86041
TAL-1BETA/ITF-2 heart 6.78146
DBP soft_tissue 6.77801
TCF11 muscle 6.77279
NKX6-2 peripheral_nervous_system 6.73082
SRF eye 6.64646
AP-1 muscle 6.56346
PBX-1 muscle 6.55288
AREB6 muscle 6.50618
EF-C brain 6.46789
HNF-4 brain 6.45529
STAT5A skin 6.43766
FOXO4 kidney 6.41365
HOXA4 soft_tissue 6.3956
IPF1 peripheral_nervous_system 6.37989
ATF eye 6.25194
TAL-1BETA/E47 muscle 6.24954
SMAD-3 skin 6.20838
MEIS1 skin 6.20041

Distribution of Co-regulatory TFs

Description: this pie chart displays the distribution of co-regulatory transcription factors (TFs) in different tissues.

Color schema: the tissue with the largest percentage of co-regulatory TFs is colored dark red whereas the tissue with the smallest percentage of co-regulatory TFs is colored dark blue. Tissues with intermediate percentages of co-regulatory TFs are colored from light red to yellow and cyan and then to light blue.