Bioinformatics Lab @ Wilmer Institute, Johns Hopkins University

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SRF has 215 co-regulatory transcription factors (TFs)

Summary Table (Download Table)

Co-regulatory TF Tissue -log(P)
SRF heart 35.9479
MEF-2 muscle 30.8206
TATA muscle 29.8598
MAZ heart 25.8573
RSRFC4 muscle 23.7435
MEF-2 heart 21.8976
RSRFC4 heart 21.1323
SP3 heart 21.0334
BSAP heart 20.468
NF-E2 heart 18.9785
E2F small_intestine 18.79
AMEF-2 muscle 18.1996
AP-1 heart 17.5307
SRF larynx 17.3659
SP1 soft_tissue 16.9948
MAZR heart 16.9494
HNF-4ALPHA kidney 16.4428
AP-4 heart 16.3926
TST-1 muscle 15.3313
RSRFC4 peripheral_nervous_system 14.8561
RREB-1 muscle 14.6692
MEIS1 heart 14.0465
PU.1 heart 13.6439
E47 muscle 13.4507
TGIF heart 13.3632
RREB-1 heart 13.2095
GATA-X heart 13.1628
SRF muscle 12.9346
HEB heart 12.6273
TEF-1 muscle 12.4996
MIF-1 muscle 12.3709
NRSF heart 12.0065
E2F-1 larynx 11.9738
MYOD heart 11.9358
RB/E2F-1/DP-1 small_intestine 11.9255
BACH1 heart 11.8862
TST-1 heart 11.8639
TATA larynx 11.6752
ELK-1 small_intestine 11.6704
ALPHA-CP1 heart 11.5243
AMEF-2 heart 11.3966
OCT-1 kidney 11.3792
ARP-1 muscle 11.3155
MZF1 heart 11.2354
POU1F1 heart 11.1706
COUP-TF/HNF-4 muscle 11.1122
ZID muscle 10.8825
FXR larynx 10.8134
E2F-4/DP-1 small_intestine 10.7557
BACH1 muscle 10.68
SMAD-3 brain 10.5392
NR2E3 muscle 10.5245
HNF-1 small_intestine 10.5223
LUN-1 larynx 10.4544
MIF-1 larynx 10.4312
SMAD-4 larynx 10.3608
C-MYC/MAX muscle 10.3504
SF-1 heart 10.3035
MAZR muscle 10.285
MAZR soft_tissue 10.264
PPARALPHA/RXR-ALPHA heart 10.1479
GATA-2 heart 10.1418
SMAD-3 muscle 10.0989
CREB soft_tissue 10.0546
LUN-1 small_intestine 10.0542
HNF-3ALPHA heart 10.0079
MEF-2 peripheral_nervous_system 9.96629
NF-KAPPAB_(P65) larynx 9.8345
GATA-4 soft_tissue 9.71006
MEF-2 soft_tissue 9.66168
RREB-1 brain 9.60531
FOXO1 kidney 9.57066
TITF1 heart 9.55532
SF-1 larynx 9.55138
IPF1 peripheral_nervous_system 9.49702
TAX/CREB muscle 9.45992
LUN-1 muscle 9.43907
USF small_intestine 9.35976
MAZR peripheral_nervous_system 9.3056
FOXJ2 brain 9.24697
SMAD-4 heart 9.24643
CHX10 eye 9.21553
RSRFC4 soft_tissue 9.16871
E2F heart 9.15755
STAT3 heart 9.07857
BRN-2 heart 8.99714
NF-KAPPAB larynx 8.9813
SREBP-1 heart 8.96862
NF-KAPPAB_(P50) heart 8.87017
COUP-TF/HNF-4 heart 8.83337
MRF-2 muscle 8.77958
FREAC-4 prostate 8.75453
OCT-1 pancreas 8.73558
ZID heart 8.71671
HNF-1 kidney 8.68023
CREB peripheral_nervous_system 8.66
E47 brain 8.64753
NF-KAPPAB_(P50) larynx 8.62997
EGR-1 soft_tissue 8.62388
STAT4 kidney 8.61199
NF-AT small_intestine 8.60894
GATA-1 heart 8.57008
C-MYC/MAX heart 8.54911
NF-KAPPAB muscle 8.45874
HEB prostate 8.45194
AP-2REP heart 8.34428
AP-4 larynx 8.24415
SP1 peripheral_nervous_system 8.22054
C/EBP larynx 8.21626
ERR_ALPHA larynx 8.14905
NF-KAPPAB_(P50) muscle 8.13258
USF heart 8.09961
HMG_IY small_intestine 8.05183
MTF-1 heart 8.02008
AP-1 muscle 8.00094
BRN-2 larynx 7.96699
C/EBPALPHA prostate 7.94899
NF-KAPPAB_(P65) heart 7.92895
STAT6 heart 7.905
TEF muscle 7.8435
HNF-1 heart 7.83853
HIF-1 brain 7.77983
PEA3 small_intestine 7.74605
GCNF small_intestine 7.73213
FOXD3 muscle 7.7301
POU3F2 uterus 7.67881
NF-1 larynx 7.67747
GCNF stomach 7.67224
GATA-3 muscle 7.67081
GATA-6 heart 7.66116
CDP_CR3+HD muscle 7.64551
OCT-1 brain 7.57459
BACH2 peripheral_nervous_system 7.56494
PITX2 muscle 7.54654
MEIS1 brain 7.50553
FAC1 pancreas 7.4837
ELF-1 small_intestine 7.4698
E2F larynx 7.46849
BSAP larynx 7.46686
FREAC-2 kidney 7.46519
MEF-2 larynx 7.44835
IRF-7 peripheral_nervous_system 7.4338
YY1 heart 7.40664
STAT5A kidney 7.39758
FOXJ2 pancreas 7.32637
CDP_CR3+HD testis 7.30741
WHN small_intestine 7.28531
SREBP-1 muscle 7.2686
NF-E2 bone 7.26027
OCT-1 prostate 7.23276
LHX3 stomach 7.23197
TAL-1BETA/ITF-2 muscle 7.2139
ZID small_intestine 7.20726
TAX/CREB soft_tissue 7.18248
P53 larynx 7.15712
ER muscle 7.13334
MTF-1 lung 7.1327
CHX10 larynx 7.12042
ETF larynx 7.07465
HSF1 muscle 7.04085
C/EBP heart 6.99639
NKX2-2 kidney 6.96699
AP-4 prostate 6.96416
PAX-3 peripheral_nervous_system 6.96095
NF-KAPPAB_(P65) soft_tissue 6.93176
PITX2 heart 6.90899
AP-2GAMMA larynx 6.88943
PU.1 muscle 6.87366
GATA-1 brain 6.86692
USF muscle 6.83697
GCM brain 6.83258
HNF-4ALPHA muscle 6.82433
TFIIA soft_tissue 6.79976
FREAC-2 peripheral_nervous_system 6.78121
STAT6 lung 6.77474
FOXO3 kidney 6.71829
TFII-I prostate 6.69261
ARNT heart 6.67369
CDC5 muscle 6.66624
PITX2 eye 6.64646
HSF kidney 6.64636
LUN-1 soft_tissue 6.61047
POU3F2 pancreas 6.59327
E2F-1 bone_marrow 6.58996
PEA3 bone_marrow 6.58852
TFIIA prostate 6.54199
HNF-3ALPHA liver 6.52607
ER brain 6.51427
NERF1A muscle 6.47593
C/EBPBETA peripheral_nervous_system 6.45924
LBP-1 heart 6.4409
GR larynx 6.4367
IPF1 heart 6.43286
PAX-3 soft_tissue 6.42872
NRL peripheral_nervous_system 6.41224
C-ETS-1 heart 6.38457
TITF1 small_intestine 6.36596
CDP brain 6.35253
LHX3 small_intestine 6.34799
CRX kidney 6.3439
AP-2 small_intestine 6.31309
TAL-1BETA/E47 heart 6.30843
AP-1 small_intestine 6.29627
NKX2-2 larynx 6.28901
GR pancreas 6.27337
HNF-1 skin 6.271
CDP_CR3 muscle 6.26818
GATA-4 small_intestine 6.2396
LMO2_COMPLEX muscle 6.23754
BRN-2 muscle 6.22437
CART-1 stomach 6.21877
NKX6-2 small_intestine 6.21712
IRF1 muscle 6.19996
TBP soft_tissue 6.19841
PBX-1 skin 6.19359

Distribution of Co-regulatory TFs

Description: this pie chart displays the distribution of co-regulatory transcription factors (TFs) in different tissues.

Color schema: the tissue with the largest percentage of co-regulatory TFs is colored dark red whereas the tissue with the smallest percentage of co-regulatory TFs is colored dark blue. Tissues with intermediate percentages of co-regulatory TFs are colored from light red to yellow and cyan and then to light blue.