Bioinformatics Lab @ Wilmer Institute, Johns Hopkins University

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AP-1 has 142 co-regulatory transcription factors (TFs)

Summary Table (Download Table)

Co-regulatory TF Tissue -log(P)
MEF-2 heart 30.334
NF-E2 larynx 29.7612
MEF-2 muscle 29.5379
RSRFC4 muscle 28.2852
RSRFC4 heart 24.1287
AP-1 larynx 19.111
SRF heart 17.5307
TCF11/MAFG larynx 15.9679
TATA heart 15.787
TATA muscle 15.6531
ALX-4 heart 15.2231
TAL-1BETA/ITF-2 muscle 14.9887
AMEF-2 muscle 14.8992
NF-E2 eye 14.3266
AP-1 muscle 13.9547
NF-E2 lymph_node 12.4413
AMEF-2 heart 12.2872
SREBP-1 bladder 12.1538
MEIS1 muscle 11.8955
TAL-1BETA/E47 muscle 11.6618
LUN-1 muscle 11.5777
TAL-1ALPHA/E47 muscle 11.1144
HNF-1 colon 11.1132
GR larynx 10.8693
BACH1 eye 10.7879
PITX2 heart 10.7507
BACH1 muscle 10.6465
CRX bladder 10.5385
GATA-6 heart 10.4322
ERR_ALPHA muscle 10.2272
IRF1 heart 10.1501
C/EBP blood 10.1369
PEA3 bone_marrow 9.89696
HNF-1 kidney 9.83536
COUP-TF/HNF-4 larynx 9.83522
LHX3 small_intestine 9.6973
GATA-X heart 9.62168
CDP_CR3+HD heart 9.59479
BACH1 larynx 9.52952
AP-1 tongue 9.4791
ELF-1 blood 9.31453
ER larynx 9.2549
CACCC-BINDING_FACTOR larynx 9.00534
TCF-4 small_intestine 8.95968
HFH-3 peripheral_nervous_system 8.86476
BACH2 lymph_node 8.83856
CRE-BP1/C-JUN muscle 8.83334
AP-1 stomach 8.64303
AP-1 eye 8.5922
ELF-1 tongue 8.58598
POU3F2 heart 8.5752
PU.1 larynx 8.55527
AP-1 lymph_node 8.51192
HAND1/E47 muscle 8.51149
BACH2 tongue 8.50456
ELF-1 lymph_node 8.49326
OCT-1 heart 8.4749
TGIF heart 8.28112
FAC1 larynx 8.26435
BACH2 stomach 8.14078
TAL-1BETA/ITF-2 eye 8.07045
NF-E2 tongue 8.04093
ER muscle 8.02658
NF-E2 bone 8.01267
SRF muscle 8.00094
TAL-1BETA/E47 eye 7.94013
AP-1 bladder 7.83842
FREAC-4 prostate 7.80358
BACH1 lymph_node 7.79824
LBP-1 spleen 7.7235
VDR spleen 7.71787
ATF-1 bone_marrow 7.69703
MEIS1B/HOXA9 heart 7.68813
LUN-1 heart 7.64279
MAZ muscle 7.57344
C-MYB heart 7.54639
FOXO4 prostate 7.53525
C/EBPDELTA heart 7.52587
GCNF muscle 7.51146
PEA3 blood 7.47036
STAT5A_(HOMODIMER) larynx 7.38366
ELK-1 bone_marrow 7.37036
FAC1 tongue 7.3398
MEF-2 bone 7.29611
TAX/CREB tongue 7.29416
AREB6 stomach 7.26764
MAZ skin 7.2102
OCT-X colon 7.19265
TST-1 heart 7.1602
CDP heart 7.14317
LBP-1 heart 7.10612
AR muscle 7.1013
MAZ larynx 7.09968
SRY prostate 7.00447
TEL-2 blood 6.98997
MEF-2 eye 6.98938
PBX1B skin 6.91814
AREB6 larynx 6.88341
PPARG lymph_node 6.88132
LEF-1 stomach 6.85325
RB/E2F-1/DP-1 larynx 6.78802
MEIS1 tongue 6.75025
STATX lymph_node 6.74698
TBP eye 6.72865
VDR larynx 6.72746
ETF ovary 6.72
TCF-4 bladder 6.67226
FREAC-7 kidney 6.64798
RSRFC4 eye 6.61931
NF-E2 prostate 6.61917
ELK-1 blood 6.61462
TFIIA muscle 6.56589
PITX2 muscle 6.56346
OSF2 blood 6.5591
AML-1A blood 6.54398
AML1 blood 6.54398
BACH1 bone 6.52062
HSF1 bladder 6.50787
FAC1 mammary_gland 6.50488
LMO2_COMPLEX heart 6.49555
TATA tongue 6.46736
STAT5A eye 6.42239
SMAD-4 stomach 6.40234
PPARG muscle 6.39834
AP-1 bone 6.38892
BACH1 stomach 6.36459
ALPHA-CP1 muscle 6.36128
LMO2_COMPLEX prostate 6.33514
C/EBPBETA heart 6.32125
MEF-2 bladder 6.31187
EF-C stomach 6.30344
PPAR blood 6.30017
SRF small_intestine 6.29627
TCF11/MAFG eye 6.28873
TFIIA bone 6.27502
STAT3 stomach 6.27021
GATA-1 heart 6.26132
RP58 eye 6.23095
EF-C bone 6.21679
C/EBP liver 6.20305
AP-4 heart 6.20041
ETF mammary_gland 6.19564

Distribution of Co-regulatory TFs

Description: this pie chart displays the distribution of co-regulatory transcription factors (TFs) in different tissues.

Color schema: the tissue with the largest percentage of co-regulatory TFs is colored dark red whereas the tissue with the smallest percentage of co-regulatory TFs is colored dark blue. Tissues with intermediate percentages of co-regulatory TFs are colored from light red to yellow and cyan and then to light blue.