|Bioinformatics Lab @ Wilmer Institute, Johns Hopkins University|
TiGER is a database developed by the Bioinformatics Lab at Wilmer Eye
Institute of Johns Hopkins University. The database contains tissue-specific
gene expression profiles or expressed sequence tag (EST) data, cis-regulatory module (CRM) data, and
combinatorial gene regulation data. Learn more about
To download the raw data files, click here. To search the database, use the following three views:
Gene ViewEnter a RefSeq gene (e.g., NM_052964), a UniGene (e.g., Hs.2182) or a gene symbol (e.g., myod1):
Transcription Factor ViewEnter a transcription factor name:
Tissue ViewSelect a tissue:
1. Liu, X., Yu, X., Zack, D.J., Zhu, H., Qian, J. (2008) TiGER: a database for tissue-specific gene expression and regulation. BMC Bioinformatics. 9:271.
2. Yu, X., Lin, J., Zack, D.J., Qian, J. (2007) Identification of tissue-specific cis-regulatory modules based on interactions between transcription factors. BMC Bioinformatics. 8:437.
3. Yu, X., Lin, J., Zack, D.J., Qian, J. (2006) Computational analysis of tissue-specific combinatorial gene regulation: predicting interaction between transcription factors in human tissues. Nucleic Acids Res. 34, 4925–4936.
4. Yu, X., Lin, J., Masuda, T., Esumi, N., Zack, D.J., Qian, J. (2006) Genome-wide prediction and characterization of interactions between transcription factors in Saccharomyces cerevisiae. Nucleic Acids Res. 34, 917–927.
Contact: Jiang Qian (firstname.lastname@example.org)