Bioinformatics Lab @ Wilmer Institute, Johns Hopkins University

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E2F has 160 co-regulatory transcription factors (TFs)

Summary Table (Download Table)

Co-regulatory TF Tissue -log(P)
SRF small_intestine 18.79
NRF-1 bladder 17.283
NRF-1 bone_marrow 13.4771
NRF-1 blood 12.2319
SRY mammary_gland 12.1579
MAZR tongue 12.0398
NRF-1 testis 11.7845
ATF bone 11.6301
OCT-1 small_intestine 10.7382
TAX/CREB thymus 10.6281
RB/E2F-1/DP-1 larynx 10.4386
NRF-1 liver 10.4303
SP1 tongue 10.3601
E2F-1 larynx 10.2694
MAZR larynx 10.1355
LHX3 placenta 10.1275
C-REL small_intestine 10.094
STAT1 bone_marrow 10.0928
ETF brain 10.0124
SP3 tongue 9.89362
AHR/ARNT cervix 9.88729
ELK-1 small_intestine 9.79841
ETF bladder 9.748
NRF-1 tongue 9.72467
E2F larynx 9.6834
NF-Y small_intestine 9.52444
E2F-1/DP-2 bone_marrow 9.47278
C/EBP tongue 9.44361
NERF1A small_intestine 9.43662
STAT5A_(HOMOTETRAMER) soft_tissue 9.43165
MZF1 tongue 9.22184
TEF brain 9.17533
RB/E2F-1/DP-1 cervix 9.16392
SRF heart 9.15755
ETF blood 9.00351
C-MYC/MAX cervix 8.93122
NKX6-2 skin 8.93057
POU3F2 small_intestine 8.87476
E2F-4/DP-1 larynx 8.85839
SP1 testis 8.83013
AP-2REP brain 8.80768
RB/E2F-1/DP-1 soft_tissue 8.78257
HIF-1 tongue 8.78114
ELK-1 testis 8.76633
SMAD-4 brain 8.76484
C-REL soft_tissue 8.76071
NRF-1 small_intestine 8.73561
SP1 small_intestine 8.73083
ATF tongue 8.65754
GATA-3 tongue 8.6505
E2F-4/DP-2 bone_marrow 8.62032
WHN larynx 8.61695
WHN small_intestine 8.59886
E2F-1 cervix 8.58064
RREB-1 muscle 8.55341
E2F cervix 8.44077
E2F-4/DP-2 larynx 8.43504
PAX-2 tongue 8.41089
PEA3 small_intestine 8.40758
TST-1 mammary_gland 8.39612
NF-KAPPAB thymus 8.3388
MTF-1 brain 8.3386
HMG_IY small_intestine 8.16905
ELK-1 cervix 8.14688
ICSBP heart 8.13784
GCM brain 8.11225
PPARG cervix 8.10307
IRF-7 small_intestine 8.03113
CREB tongue 8.02428
MZF1 brain 7.98216
GR soft_tissue 7.93577
VDR small_intestine 7.89615
TAL-1ALPHA/E47 small_intestine 7.84027
E2F-4/DP-1 bone_marrow 7.82594
E2F-4/DP-1 cervix 7.80984
YY1 larynx 7.79913
AP-2ALPHA small_intestine 7.71325
RB/E2F-1/DP-1 bone_marrow 7.71267
AHR/ARNT ovary 7.70089
NF-Y larynx 7.64205
RREB-1 small_intestine 7.63295
NF-KAPPAB soft_tissue 7.60532
TST-1 small_intestine 7.58315
LXR heart 7.58039
E2F-1/DP-2 larynx 7.47891
SRF larynx 7.46849
AR larynx 7.45978
TFII-I larynx 7.43691
ATF testis 7.43061
VDR ovary 7.42501
NRF-1 cervix 7.42151
E2F-1/DP-1 bone_marrow 7.41167
NRF-1 lung 7.40541
E2F-1 bone_marrow 7.36917
NF-E2 bone 7.27355
CACCC-BINDING_FACTOR cervix 7.22264
E47 small_intestine 7.17335
E2F-1 soft_tissue 7.16824
ETF bone_marrow 7.16214
CHX10 larynx 7.12882
SRY lung 7.12503
NF-Y testis 7.12092
HEB small_intestine 7.07722
P53 brain 7.05188
TAL-1BETA/E47 heart 7.00068
AP-2 small_intestine 6.98099
STAT5A_(HOMOTETRAMER) thymus 6.98045
PAX-3 small_intestine 6.96861
NF-Y lymph_node 6.9638
ETF placenta 6.94098
CRE-BP1/C-JUN tongue 6.88526
DBP soft_tissue 6.87831
NF-AT tongue 6.86875
SREBP-1 tongue 6.8594
TATA small_intestine 6.77628
AHR/ARNT small_intestine 6.76968
GABP testis 6.74807
CDP_CR1 lung 6.7402
ZID small_intestine 6.71442
E2F-1/DP-1 larynx 6.6575
ETF small_intestine 6.62234
NRF-1 larynx 6.62048
NF-KAPPAB_(P50) lung 6.5732
E2F-1 testis 6.57047
NF-KAPPAB_(P65) soft_tissue 6.54202
E2F-1 thymus 6.50358
MEF-2 lung 6.50225
E4F1 peripheral_nervous_system 6.48544
CDP heart 6.46737
CREB cervix 6.46009
E2F bone_marrow 6.45693
FOXD3 heart 6.44101
PBX-1 mammary_gland 6.43361
PPARG small_intestine 6.40023
CDP_CR3+HD soft_tissue 6.40008
RFX1 small_intestine 6.39536
PAX-8 brain 6.36678
LF-A1 bone 6.35387
C/EBP brain 6.34894
CRE-BP1 tongue 6.34458
ALPHA-CP1 small_intestine 6.34305
NF-KAPPAB_(P50) soft_tissue 6.34047
C-MYC/MAX larynx 6.33667
AP-2GAMMA lung 6.32672
AP-2 cervix 6.31968
USF2 tongue 6.3182
OCT-1 ovary 6.29904
NRF-1 lymph_node 6.28331
STAT1 tongue 6.27735
IRF1 thymus 6.2741
NF-Y tongue 6.27284
RB/E2F-1/DP-1 thymus 6.25593
ATF peripheral_nervous_system 6.24974
OCT-1 tongue 6.24954
BSAP tongue 6.23382
C-MYB small_intestine 6.22389
GR bone 6.19512
BACH2 small_intestine 6.19168
GR thymus 6.17765
ETF testis 6.17184

Distribution of Co-regulatory TFs

Description: this pie chart displays the distribution of co-regulatory transcription factors (TFs) in different tissues.

Color schema: the tissue with the largest percentage of co-regulatory TFs is colored dark red whereas the tissue with the smallest percentage of co-regulatory TFs is colored dark blue. Tissues with intermediate percentages of co-regulatory TFs are colored from light red to yellow and cyan and then to light blue.