Bioinformatics Lab @ Wilmer Institute, Johns Hopkins University

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FXR has 38 co-regulatory transcription factors (TFs)

Summary Table (Download Table)

Co-regulatory TF Tissue -log(P)
AFP1 blood 8.36242
FOXJ2 blood 6.48548
MEF-2 blood 6.79103
PEA3 blood 6.29979
OCT-1 bone 6.35942
FREAC-3 brain 6.23361
CHX10 eye 11.6646
CRX eye 12.8655
FOXJ2 eye 6.34719
PITX2 eye 8.9686
C/EBP heart 6.66998
C/EBPBETA heart 6.56962
FREAC-2 heart 6.20791
GATA-1 heart 6.18204
GATA-6 heart 6.17868
GATA-X heart 6.7543
HNF-3ALPHA heart 7.61186
ICSBP heart 6.29072
STAT4 heart 8.42028
TCF11/MAFG heart 6.39253
CRX kidney 6.75061
HNF-1 kidney 10.6536
SRF larynx 10.8134
C/EBPBETA liver 6.8881
C/EBPDELTA liver 7.65913
GATA-6 liver 7.31563
HNF-1 liver 7.45405
RP58 liver 6.20728
MEF-2 muscle 12.2967
RSRFC4 muscle 10.6385
ETF ovary 6.40494
HNF-1 ovary 6.72474
HNF-3ALPHA soft_tissue 7.56108
TBP stomach 7.44639
BACH1 tongue 9.04888
C-MYC/MAX tongue 8.00453
NF-KAPPAB tongue 7.09198
NF-KAPPAB_(P50) tongue 8.10137

Distribution of Co-regulatory TFs

Description: this pie chart displays the distribution of co-regulatory transcription factors (TFs) in different tissues.

Color schema: the tissue with the largest percentage of co-regulatory TFs is colored dark red whereas the tissue with the smallest percentage of co-regulatory TFs is colored dark blue. Tissues with intermediate percentages of co-regulatory TFs are colored from light red to yellow and cyan and then to light blue.