| Bioinformatics Lab @ Wilmer Institute, Johns Hopkins University |
TiGER is a database developed by the Bioinformatics Lab at Wilmer Eye
Institute of Johns Hopkins University. The database contains tissue-specific
gene expression profiles or expressed sequence tag (EST) data, cis-regulatory module (CRM) data, and
combinatorial gene regulation data. Learn more about
the database.
To download
the raw data files, click
here.
To search the database, use the following three views:
Gene View
Enter a RefSeq gene (e.g., NM_052964), a UniGene (e.g., Hs.2182) or a gene symbol (e.g., myod1):
Transcription Factor View
Enter a transcription factor name:
Tissue View
Select a tissue:
References
1. Liu, X., Yu, X., Zack, D.J., Zhu, H., Qian, J. (2008)
TiGER: a
database for tissue-specific gene expression and regulation.
BMC Bioinformatics. 9:271.
2. Yu, X., Lin, J., Zack, D.J., Qian, J. (2007)
Identification of tissue-specific cis-regulatory
modules based on interactions between transcription factors. BMC Bioinformatics.
8:437.
3. Yu, X., Lin, J., Zack, D.J., Qian, J. (2006)
Computational analysis of tissue-specific combinatorial gene regulation: predicting interaction between transcription factors in human tissues.
Nucleic Acids Res. 34, 4925–4936.
4. Yu, X., Lin, J., Masuda, T., Esumi, N., Zack, D.J., Qian, J. (2006)
Genome-wide prediction and characterization of interactions between transcription factors in
Saccharomyces cerevisiae. Nucleic Acids Res. 34, 917–927.
Contact: Jiang Qian (jiang.qian@jhmi.edu)