WAS is a predicted scaffold protein, which is related to the following pathway(s).

BTK->ITK->TEC
FGR->CSNK2A1->HCLS1
SRC->EGFR->GRB2
SRC->EGFR->PLCG1


WAS is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
PLCG1LYN->BTK->WAS
PLCG1PDGFRA->SRC->ABL1->BTK->WAS
TECLYN->BTK->WAS
HCLS1FGR->CSNK2A1->WAS
HCLS1LYN->CSNK2A1->WAS


The sequence of WAS

Amino acids in red are phosphorylation sites determined by MS/MS

MSGGPMGGRP GGRGAPAVQQ NIPSTLLQDH ENQRLFEMLG RKCLTLATAV 50
VQLYLALPPG AEHWTKEHCG AVCFVKDNPQ KSYFIRLYGL QAGRLLWEQE 100
LYSQLVYSTP TPFFHTFAGD DCQAGLNFAD EDEAQAFRAL VQEKIQKRNQ 150
RQSGDRRQLP PPPTPANEER RGGLPPLPLH PGGDQGGPPV GPLSLGLATV 200
DIQNPDITSS RYRGLPAPGP SPADKKRSGK KKISKADIGA PSGFKHVSHV 250
GWDPQNGFDV NNLDPDLRSL FSRAGISEAQ LTDAETSKLI YDFIEDQGGL 300
EAVRQEMRRQ EPLPPPPPPS RGGNQLPRPP IVGGNKGRSG PLPPVPLGIA 350
PPPPTPRGPP PPGRGGPPPP PPPATGRSGP LPPPPPGAGG PPMPPPPPPP 400
PPPPSSGNGP APPPLPPALV PAGGLAPGGG RGALLDQIRQ GIQLNKTPGA 450
PESSALQPPP QSSEGLVGAL MHVMQKRSRA IHSSDEGEDQ AGDEDEDDEW 500
DD

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