TP53 is a predicted scaffold protein, which is related to the following pathway(s).

HIPK2->TP53
ATM->CHEK1->TP53
ATM->CHEK2->TP53


TP53 is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
MDC1ATM->CHEK2->TP53
BRCA1CSNK2A1->CDC2->CDK7->TP53
PLK3CHEK2->TP53
TP53INP1HIPK2->TP53
CDC25CPLK1->CHEK2->TP53
CCNHCDK2->CDK7->TP53
ERCC6CHEK2->TP53
BLMATM->CHEK1->TP53
TP53BP1ATM->CHEK1->TP53
TP53BP1ATM->CHEK2->TP53
MDM4ATM->CHEK1->TP53
MDM4ATM->CHEK2->TP53
ERCC2CDC2->CDK7->TP53


The sequence of TP53

Amino acids in red are phosphorylation sites determined by MS/MS

MEEPQSDPSV EPPLSQETFS DLWKLLPENN VLSPLPSQAM DDLMLSPDDI 50
EQWFTEDPGP DEAPRMPEAA PRVAPAPAAP TPAAPAPAPS WPLSSSVPSQ 100
KTYQGSYGFR LGFLHSGTAK SVTCTYSPAL NKMFCQLAKT CPVQLWVDST 150
PPPGTRVRAM AIYKQSQHMT EVVRRCPHHE RCSDSDGLAP PQHLIRVEGN 200
LRVEYLDDRN TFRHSVVVPY EPPEVGSDCT TIHYNYMCNS SCMGGMNRRP 250
ILTIITLEDS SGNLLGRNSF EVRVCACAGR DRRTEEENLR KKGEPHHELP 300
PGSTKRALPN NTSSSPQPKK KPLDGEYFTL QIRGRERFEM FRELNEALEL 350
KDAQAGKEPG GSRAHSSHLK SKKGQSTSRH KKLMFKTEGP DSD 400

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