TANC1 is a known scaffold protein, which is related to the following pathway(s).
| DLGAP4 | -> | DLG1 |
Reference:A novel scaffold protein, TANC, possibly a rat homolog of Drosophila rolling pebbles (rols), forms a multiprotein complex with various postsynaptic density proteins.
PMID:15673434
The sequence of TANC1
Amino acids in red are phosphorylation sites determined by MS/MS
MLKAVLKKSR EGGKGGKKEA GSDFGPETSP VLHLDHSADS PVSSLPTAED 50
TYRVSLAKGV SMSLPSSPLL PRQSHLVQSR VNKKSPGPVR KPKYVESPRV 100
PGDAVIMPFR EVAKPTEPDE HEAKADNEPS CSPAAQELLT RLGFLLGEGI 150
PSATHITIED KNETMCTALS QGISPCSTLT SSTASPSTDS PCSTLNSCVS 200
KTAANKSPCE TISSPSSTLE SKDSGIIATI TSSSENDDRS GSSLEWNKDG 250
SLRLGVQKGV LHDRRADNCS PVAEEETTGS AESTLPKAES SAGDGPVPYS 300
QGSSSLIMPR PNSVAATSST KLEDLSYLDG QRNAPLRTSI RLPWHNTAGG 350
RAQEVKARFA PYKPQDILLK PLLFEVPSIT TDSVFVGRDW LFHQIEENLR 400
NTELAENRGA VVVGNVGFGK TAIISKLVAL SCHGSRMRQI ASNSPGSSPK 450
TSDPTQDLHF TPLLSPSSST SASSTAKTPL GSISAENQRP REDAVKYLAS 500
KVVAYHYCQA DNTYTCLVPE FVHSIAALLC RSHQLAAYRD LLIKEPQLQS 550
MLSLRSCVQD PVAAFKRGVL EPLTNLRNEQ KIPEEEYIIL IDGLNEAEFH 600
KPDYGDTLSS FITKIISKFP AWLKLIVTVR ANFQEIISAL PFVKLSLDDF 650
PDNKDIHSDL HAYVQHRVHS SQDILSNISL NGKADATLIG KVSSHLVLRS 700
LGSYLYLKLT LDLFQRGHLV IKSASYKVVP VSLSELYLLQ CNMKFMTQSA 750
FERALPILNV ALASLHPMTD EQIFQAINAG HIQGEQGWED FQQRMDALSC 800
FLIKRRDKTR MFCHPSFREW LVWRADGENT AFLCEPRNGH ALLAFMFSRQ 850
EGKLNRQQTM ELGHHILKAH IFKGLSKKTG ISSSHLQALW IGYSTEGLSA 900
ALASLRNLYT PNVKVSRLLI LGGANVNYRT EVLNNAPILC VQSHLGHEEV 950
VTLLLEFGAC LDGTSENGMT ALCYAAAAGH MKLVCLLTKK GVRVDHLDKK 1000
GQCALVHSAL RGHGDILQYL LTCEWSPGPP QPGTLRKSHA LQQALTAAAS 1050
MGHSSVVQCL LGMEKEHEVE VNGTDTLWGE TALTAAAGRG KLEVCELLLG 1100
HGAAVSRTNR RGVPPLFCAA RQGHWQIVRL LLERGCDVNL SDKQGRTPLM 1150
VAACEGHLST VEFLLSKGAA LSSLDKEGLS ALSWACLKGH RAVVQYLVEE 1200
GAAIDQTDKN GRTPLDLAAF YGDAETVLYL VEKGAVIEHV DHSGMRPLDR 1250
AIGCRNTSVV VALLRKGAKL GNAAWAMATS KPDILIILLQ KLMEEGNVMY 1300
KKGKMKEAAQ RYQYALRKFP REGFGEDMRP FNELRVSLYL NLSRCRRKTN 1350
DFGMAEEFAS KALELKPKSY EAFYARARAK RNSRQFVAAL ADLQEAVKLC 1400
PTNQEVKRLL ARVEEECKQL QRSQQQKQQG PLPAPLNDSE NEEDTPTPGL 1450
SDHFHSEETE EEETSPQEES VSPTPRSQPS SSVPSSYIRN LQEGLQSKGR 1500
PVSPQSRAGI GKSLREPVAQ PGLLLQPSKQ AQIVKTSQHL GSGQSAVRNG 1550
SMKVQISSQN PPPSPMPGRI AATPAGSRTQ HLEGTGTFTT RAGCGHFGDR 1600
LGPSQNVRLQ CGENGPAHPL PSKTKTTERL LSHSSVAVDA APPNQGGLAT 1650
CSDVRHPASL TSSGSSGSPS SSIKMSSSTS SLTSSSSFSD GFKVQGPDTR 1700
IKDKVVTHVQ SGTAEHRPRN TPFMGIMDKT ARFQQQSNPP SRSWHCPAPE 1750
GLLTNTSSAA GLQSANTEKP SLMQVGGYNN QAKTCSVSTL SASVHNGAQV 1800
KELEESKCQI PVHSQENRIT KTVSHLYQES ISKQQPHISN EAHRSHLTAA 1850
KPKRSFIESN V