STAT3 is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
CXCR4JAK3->JAK1->STAT3
HES5JAK2->STAT3
PTPN11PDGFRA->SRC->STAT3
STAT5BJAK3->JAK1->STAT3
STAT5BPDGFRA->SRC->STAT3
IGF1RCSK->SRC->STAT3
STAP2JAK2->STAT3
STAP2SRC->STAT3
STAT5AJAK3->JAK1->STAT3
STAT5APDGFRA->SRC->STAT3
PTPN2CDK5->SRC->STAT3
PTPN2JAK3->JAK1->STAT3
IL23RJAK2->STAT3
IL7RJAK3->JAK1->STAT3
PDGFRBPDGFRA->SRC->STAT3
STATIP1JAK1->STAT3
STATIP1JAK2->STAT3
IL2RBJAK3->JAK1->STAT3


The sequence of STAT3

Amino acids in red are phosphorylation sites determined by MS/MS

MAQWNQLQQL DTRYLEQLHQ LYSDSFPMEL RQFLAPWIES QDWAYAASKE 50
SHATLVFHNL LGEIDQQYSR FLQESNVLYQ HNLRRIKQFL QSRYLEKPME 100
IARIVARCLW EESRLLQTAA TAAQQGGQAN HPTAAVVTEK QQMLEQHLQD 150
VRKRVQDLEQ KMKVVENLQD DFDFNYKTLK SQGDMQDLNG NNQSVTRQKM 200
QQLEQMLTAL DQMRRSIVSE LAGLLSAMEY VQKTLTDEEL ADWKRRQQIA 250
CIGGPPNICL DRLENWITSL AESQLQTRQQ IKKLEELQQK VSYKGDPIVQ 300
HRPMLEERIV ELFRNLMKSA FVVERQPCMP MHPDRPLVIK TGVQFTTKVR 350
LLVKFPELNY QLKIKVCIDK DSGDVAALRG SRKFNILGTN TKVMNMEESN 400
NGSLSAEFKH LTLREQRCGN GGRANCDASL IVTEELHLIT FETEVYHQGL 450
KIDLETHSLP VVVISNICQM PNAWASILWY NMLTNNPKNV NFFTKPPIGT 500
WDQVAEVLSW QFSSTTKRGL SIEQLTTLAE KLLGPGVNYS GCQITWAKFC 550
KENMAGKGFS FWVWLDNIID LVKKYILALW NEGYIMGFIS KERERAILST 600
KPPGTFLLRF SESSKEGGVT FTWVEKDISG KTQIQSVEPY TKQQLNNMSF 650
AEIIMGYKIM DATNILVSPL VYLYPDIPKE EAFGKYCRPE SQEHPEADPG 700
AAPYLKTKFI CVTPTTCSNT IDLPMSPRTL DSLMQFGNNG EGAEPSAGGQ 750
FESLTFDMEL TSECATSPM

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