SQSTM1 is a known scaffold protein, which is related to the following pathway(s).
| PRKCI | -> | ERK | -> | RIP1 | -> | TRAF6 |
Reference:Signal integration and diversification through the p62 scaffold protein.
PMID:17174552
The sequence of SQSTM1
Amino acids in red are phosphorylation sites determined by MS/MS
MASLTVKAYL LGKEDAAREI RRFSFCCSPE PEAEAEAAAG PGPCERLLSR 50
VAALFPALRP GGFQAHYRDE DGDLVAFSSD EELTMAMSYV KDDIFRIYIK 100
EKKECRRDHR PPCAQEAPRN MVHPNVICDG CNGPVVGTRY KCSVCPDYDL 150
CSVCEGKGLH RGHTKLAFPS PFGHLSEGFS HSRWLRKVKH GHFGWPGWEM 200
GPPGNWSPRP PRAGEARPGP TAESASGPSE DPSVNFLKNV GESVAAALSP 250
LGIEVDIDVE HGGKRSRLTP VSPESSSTEE KSSSQPSSCC SDPSKPGGNV 300
EGATQSLAEQ MRKIALESEG RPEEQMESDN CSGGDDDWTH LSSKEVDPST 350
GELQSLQMPE SEGPSSLDPS QEGPTGLKEA ALYPHLPPEA DPRLIESLSQ 400
MLSMGFSDEG GWLTRLLQTK NYDIGAALDT IQYSKHPPPL 450