RPS6KB1 is a predicted scaffold protein, which is related to the following pathway(s).

CDC2->CSNK2A1->AKT1
CDC2->CSNK2A1->MAPK9
LYN->CSNK2A1->AKT1
LYN->CSNK2A1->MAPK9
LYN->CSNK2A1->CDC2->CSNK2B


RPS6KB1 is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
EIF4EFRAP1->RPS6KB1->EIF4B
EIF4ERPS6KB1->FRAP1->EIF4EBP1
EIF3BFRAP1->RPS6KB1
EIF3BRPS6KB1->FRAP1
PPP2R2ARPS6KB1->FRAP1->EIF4EBP1
NCBP1FRAP1->RPS6KB1->POLDIP3
GDI2PFRAP1->RPS6KB1
GDI2PRPS6KB1->FRAP1
EIF3S9FRAP1->RPS6KB1->EIF4B


The sequence of RPS6KB1

Amino acids in red are phosphorylation sites determined by MS/MS

MRRRRRRDGF YPAPDFRDRE AEDMAGVFDI DLDQPEDAGS EDELEEGGQL 50
NESMDHGGVG PYELGMEHCE KFEISETSVN RGPEKIRPEC FELLRVLGKG 100
GYGKVFQVRK VTGANTGKIF AMKVLKKAMI VRNAKDTAHT KAERNILEEV 150
KHPFIVDLIY AFQTGGKLYL ILEYLSGGEL FMQLEREGIF MEDTACFYLA 200
EISMALGHLH QKGIIYRDLK PENIMLNHQG HVKLTDFGLC KESIHDGTVT 250
HTFCGTIEYM APEILMRSGH NRAVDWWSLG ALMYDMLTGA PPFTGENRKK 300
TIDKILKCKL NLPPYLTQEA RDLLKKLLKR NAASRLGAGP GDAGEVQAHP 350
FFRHINWEEL LARKVEPPFK PLLQSEEDVS QFDSKFTRQT PVDSPDDSTL 400
SESANQVFLG FTYVAPSVLE SVKEKFSFEP KIRSPRRFIG SPRTPVSPVK 450
FSPGDFWGRG ASASTANPQT PVEYPMETSG IEQMDVTMSG EASAPLPIRQ 500
PNSGPYKKQA FPMISKRPEH LRMNL

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