PRKCA is a known scaffold protein, which is related to the following pathway(s).

GRM7->PRKCA

PRKCA is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
PLD2PRKCA->EGFR->PLCG1
SHC1SYK->PRKCA->ITGB4
SHC1SYK->PRKCA->PLCG1
SHC1SYK->PRKCA->PTPN12
SHC1SYK->PRKCA->PTPN6
SHC1SYK->PRKCA->EGFR->CBL
SHC1SYK->PRKCA->EGFR->CRK
SHC1SYK->PRKCA->EGFR->GAB1
SHC1SYK->PRKCA->EGFR->GRB2
SHC1SYK->PRKCA->EGFR->PLCG1
SHC1SYK->PRKCA->EGFR->RASA1
SHC1SYK->PRKCA->EGFR->STAT5B
SHC1SYK->PRKCA->INSR->CBL
SHC1SYK->PRKCA->INSR->DOK1
SHC1SYK->PRKCA->INSR->GAB1
SHC1SYK->PRKCA->INSR->PIK3R1
NFATC1PRKCA->EP300
PTPN11PRKCA->EGFR->CBL
PTPN11PRKCA->EGFR->GAB1
PTPN11PRKCA->EGFR->GRB2
PTPN11PRKCA->EGFR->PLCG1
PTPN11PRKCA->EGFR->STAT1
PTPN11PRKCA->EGFR->STAT5B
PTPN11PRKCA->INSR->CBL
PTPN11PRKCA->INSR->GAB1
PTPN11PRKCA->INSR->PIK3R1
PTPN11PRKCA->INSR->SHC1
CBLSYK->PRKCA->CD5
CBLSYK->PRKCA->KIT
CBLSYK->PRKCA->PLCG1
CBLSYK->PRKCA->PTPN6
CBLSYK->PRKCA->SH3BP2
CBLSYK->PRKCA->EGFR->CRK
CBLSYK->PRKCA->EGFR->GRB2
CBLSYK->PRKCA->EGFR->PLCG1
CBLSYK->PRKCA->EGFR->STAT5B
CBLSYK->PRKCA->EGFR->VAV2
CBLSYK->PRKCA->INSR->PIK3R1
CBLSYK->PRKCA->INSR->SHC1
FASPRKCA->EGFR->CALM1
KRT18P19PRKCA->EGFR->CBL
KRT18P19PRKCA->EGFR->HGS
AKAP12PRKCA->ADRBK1->ADRB2
OPRD1PRKCA->ADRBK1->ADRB2
PTPN6SYK->PRKCA->CD5
PTPN6SYK->PRKCA->KIT
PTPN6SYK->PRKCA->MYH9
PTPN6SYK->PRKCA->EGFR->CBL
PTPN6SYK->PRKCA->EGFR->GRB2
PTPN6SYK->PRKCA->EGFR->STAT5B
PTPN6SYK->PRKCA->INSR->CBL
PTPN6SYK->PRKCA->INSR->DOK1
PTPN6SYK->PRKCA->INSR->PIK3R1
PTPN6SYK->PRKCA->INSR->SHC1
SRCSYK->PRKCA->ADRBK1->PDGFRB->PTPN11
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->CAV1
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->CBL
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->CTNNB1
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->FYB
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->GRB10
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->MAP2
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->NMT1
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->SHC1
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->SKAP1
BTKSYK->PRKCA->KIT
BTKSYK->PRKCA->PLCG1
BTKSYK->PRKCA->PRKD1
BTKSYK->PRKCA->RPS6KB2
GNA15PRKCA->ADRBK1->ADRB2
GNA15PRKCA->ADRBK1->OPRD1



PRKCA is also a known signal protein, which is involved in the following pathway(s)

Scaffold Protein(s)Related Pathway(s)PMID
PRKCABPGRM7->PRKCA12386143

Reference:Regulation of G protein-coupled receptor signaling by scaffold proteins.

PMID:12386143


The sequence of PRKCA

Amino acids in red are phosphorylation sites determined by MS/MS

MADVFPGNDS TASQDVANRF ARKGALRQKN VHEVKDHKFI ARFFKQPTFC 50
SHCTDFIWGF GKQGFQCQVC CFVVHKRCHE FVTFSCPGAD KGPDTDDPRS 100
KHKFKIHTYG SPTFCDHCGS LLYGLIHQGM KCDTCDMNVH KQCVINVPSL 150
CGMDHTEKRG RIYLKAEVAD EKLHVTVRDA KNLIPMDPNG LSDPYVKLKL 200
IPDPKNESKQ KTKTIRSTLN PQWNESFTFK LKPSDKDRRL SVEIWDWDRT 250
TRNDFMGSLS FGVSELMKMP ASGWYKLLNQ EEGEYYNVPI PEGDEEGNME 300
LRQKFEKAKL GPAGNKVISP SEDRKQPSNN LDRVKLTDFN FLMVLGKGSF 350
GKVMLADRKG TEELYAIKIL KKDVVIQDDD VECTMVEKRV LALLDKPPFL 400
TQLHSCFQTV DRLYFVMEYV NGGDLMYHIQ QVGKFKEPQA VFYAAEISIG 450
LFFLHKRGII YRDLKLDNVM LDSEGHIKIA DFGMCKEHMM DGVTTRTFCG 500
TPDYIAPEII AYQPYGKSVD WWAYGVLLYE MLAGQPPFDG EDEDELFQSI 550
MEHNVSYPKS LSKEAVSICK GLMTKHPAKR LGCGPEGERD VREHAFFRRI 600
DWEKLENREI QPPFKPKVCG KGAENFDKFF TRGQPVLTPP DQLVIANIDQ 650
SDFEGFSYVN PQFVHPILQS AV

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