MAPK8IP1 is a known scaffold protein, which is related to the following pathway(s).

HPK->MLK3->MKK7->JNK

Reference:Protein-protein interactions define specificity in signal transduction.

PMID:10809663

MAPK8IP1 is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
MAP2K7MAP3K11->MAP2K4->MAPK8->MAPK8IP1
MAP2K7MAP3K11->MAP2K4->MAPK9->MAPK8IP1
MAP2K7MAP3K5->MAP2K4->MAPK8->MAPK8IP1
MAP2K7MAP3K5->MAP2K4->MAPK9->MAPK8IP1
MAPK8IP3MAP3K1->MAP2K7->MAPK8->MAPK8IP1
MAPK8IP3MAP3K1->MAP2K7->MAPK9->MAPK8IP1
MAPK8IP3MAP3K11->MAP2K4->MAPK8->MAPK8IP1
MAPK8IP3MAP3K11->MAP2K4->MAPK9->MAPK8IP1
MAPK8IP3MAP3K5->MAP2K4->MAPK8->MAPK8IP1
MAPK8IP3MAP3K5->MAP2K4->MAPK9->MAPK8IP1
DUSP16MAPK8->MAPK8IP1
DUSP16MAPK9->MAPK8IP1
MAPK8IP2MAP2K7->MAPK8->MAPK8IP1
MAPK8IP2MAP2K7->MAPK9->MAPK8IP1


The sequence of MAPK8IP1

Amino acids in red are phosphorylation sites determined by MS/MS

MAERESGGLG GGAASPPAAS PFLGLHIASP PNFRLTHDIS LEEFEDEDLS 50
EITDECGISL QCKDTLSLRP PRAGLLSAGG GGAGSRLQAE MLQMDLIDAT 100
GDTPGAEDDE EDDDEERAAR RPGAGPPKAE SGQEPASRGQ GQSQGQSQGP 150
GSGDTYRPKR PTTLNLFPQV PRSQDTLNNN SLGKKHSWQD RVSRSSSPLK 200
TGEQTPPHEH ICLSDELPPQ SGPAPTTDRG TSTDSPCRRS TATQMAPPGG 250
PPAAPPGGRG HSHRDRIHYQ ADVRLEATEE IYLTPVQRPP DAAEPTSAFL 300
PPTESRMSVS SDPDPAAYPS TAGRPHPSIS EEEEGFDCLS SPERAEPPGG 350
GWRGSLGEPP PPPRASLSSD TSALSYDSVK YTLVVDEHAQ LELVSLRPCF 400
GDYSDESDSA TVYDNCASVS SPYESAIGEE YEEAPRPQPP ACLSEDSTPD 450
EPDVHFSKKF LNVFMSGRSR SSSAESFGLF SCIINGEEQE QTHRAIFRFV 500
PRHEDELELE VDDPLLVELQ AEDYWYEAYN MRTGARGVFP AYYAIEVTKE 550
PEHMAALAKN SDWVDQFRVK FLGSVQVPYH KGNDVLCAAM QKIATTRRLT 600
VHFNPPSSCV LEISVRGVKI GVKADDSQEA KGNKCSHFFQ LKNISFCGYH 650
PKNNKYFGFI TKHPADHRFA CHVFVSEDST KALAESVGRA FQQFYKQFVE 700
YTCPTEDIYL E

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