| Scaffold Protein(s) | Related Pathway(s) | CBL | CSK->FYN->ITCH | CBL | PDGFRB->FYN->ITCH | CBLC | FYN->ITCH |
|---|
The sequence of ITCH
Amino acids in red are phosphorylation sites determined by MS/MS
MSDSGSQLGS MGSLTMKSQL QITVISAKLK ENKKNWFGPS PYVEVTVDGQ 50
SKKTEKCNNT NSPKWKQPLT VIVTPVSKLH FRVWSHQTLK SDVLLGTAAL 100
DIYETLKSNN MKLEEVVVTL QLGGDKEPTE TIGDLSICLD GLQLESEVVT 150
NGETTCSESA SQNDDGSRSK DETRVSTNGS DDPEDAGAGE NRRVSGNNSP 200
SLSNGGFKPS RPPRPSRPPP PTPRRPASVN GSPSATSESD GSSTGSLPPT 250
NTNTNTSEGA TSGLIIPLTI SGGSGPRPLN PVTQAPLPPG WEQRVDQHGR 300
VYYVDHVEKR TTWDRPEPLP PGWERRVDNM GRIYYVDHFT RTTTWQRPTL 350
ESVRNYEQWQ LQRSQLQGAM QQFNQRFIYG NQDLFATSQS KEFDPLGPLP 400
PGWEKRTDSN GRVYFVNHNT RITQWEDPRS QGQLNEKPLP EGWEMRFTVD 450
GIPYFVDHNR RTTTYIDPRT GKSALDNGPQ IAYVRDFKAK VQYFRFWCQQ 500
LAMPQHIKIT VTRKTLFEDS FQQIMSFSPQ DLRRRLWVIF PGEEGLDYGG 550
VAREWFFLLS HEVLNPMYCL FEYAGKDNYC LQINPASYIN PDHLKYFRFI 600
GRFIAMALFH GKFIDTGFSL PFYKRILNKP VGLKDLESID PEFYNSLIWV 650
KENNIEECDL EMYFSVDKEI LGEIKSHDLK PNGGNILVTE ENKEEYIRMV 700
AEWRLSRGVE EQTQAFFEGF NEILPQQYLQ YFDAKELEVL LCGMQEIDLN 750
DWQRHAIYRH YARTSKQIMW FWQFVKEIDN EKRMRLLQFV TGTCRLPVGG 800
FADLMGSNGP QKFCIEKVGK ENWLPRSHTC FNRLDLPPYK SYEQLKEKLL 850
FAIEETEGFG QE