HRAS is a known signal protein, which is involved in the following pathway(s)
HRAS is a known signal protein, which is involved in the following pathway(s)
| Scaffold Protein(s) | Related Pathway(s) | PMID |
|---|---|---|
| CAV1 | GNAI1->HRAS->SRC | 8910575 |
| LGALS3 | HRAS->GAL | 1467850 |
Reference:Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases.
PMID:8910575
Reference:Does too much urology damage your eyesight? Study of macular function.
PMID:1467850
The sequence of HRAS
Amino acids in red are phosphorylation sites determined by MS/MS
MTEYKLVVVG AGGVGKSALT IQLIQNHFVD EYDPTIEDSY RKQVVIDGET 50
CLLDILDTAG QEEYSAMRDQ YMRTGEGFLC VFAINNTKSF EDIHQYREQI 100
KRVKDSDDVP MVLVGNKCDL AARTVESRQA QDLARSYGIP YIETSAKTRQ 150
GVEDAFYTLV REIRQHKLRK LNPPDESGPG CMSCKCVLS