FLNA is a known scaffold protein, which is related to the following pathway(s).

CAR->RAC1

Reference:Interaction of the calcium-sensing receptor and filamin, a potential scaffolding protein.

PMID:11390379

FLNA is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
MAP2K1MAPK1->PAK1->FLNA


The sequence of FLNA

Amino acids in red are phosphorylation sites determined by MS/MS

MSSSHSRAGQ SAAGAAPGGG VDTRDAEMPA TEKDLAEDAP WKKIQQNTFT 50
RWCNEHLKCV SKRIANLQTD LSDGLRLIAL LEVLSQKKMH RKHNQRPTFR 100
QMQLENVSVA LEFLDRESIK LVSIDSKAIV DGNLKLILGL IWTLILHYSI 150
SMPMWDEEED EEAKKQTPKQ RLLGWIQNKL PQLPITNFSR DWQSGRALGA 200
LVDSCAPGLC PDWDSWDASK PVTNAREAMQ QADDWLGIPQ VITPEEIVDP 250
NVDEHSVMTY LSQFPKAKLK PGAPLRPKLN PKKARAYGPG IEPTGNMVKK 300
RAEFTVETRS AGQGEVLVYV EDPAGHQEEA KVTANNDKNR TFSVWYVPEV 350
TGTHKVTVLF AGQHIAKSPF EVYVDKSQGD ASKVTAQGPG LEPSGNIANK 400
TTYFEIFTAG AGTGEVEVVI QDPMGQKGTV EPQLEARGDS TYRCSYQPTM 450
EGVHTVHVTF AGVPIPRSPY TVTVGQACNP SACRAVGRGL QPKGVRVKET 500
ADFKVYTKGA GSGELKVTVK GPKGEERVKQ KDLGDGVYGF EYYPMVPGTY 550
IVTITWGGQN IGRSPFEVKV GTECGNQKVR AWGPGLEGGV VGKSADFVVE 600
AIGDDVGTLG FSVEGPSQAK IECDDKGDGS CDVRYWPQEA GEYAVHVLCN 650
SEDIRLSPFM ADIRDAPQDF HPDRVKARGP GLEKTGVAVN KPAEFTVDAK 700
HGGKAPLRVQ VQDNEGCPVE ALVKDNGNGT YSCSYVPRKP VKHTAMVSWG 750
GVSIPNSPFR VNVGAGSHPN KVKVYGPGVA KTGLKAHEPT YFTVDCAEAG 800
QGDVSIGIKC APGVVGPAEA DIDFDIIRND NDTFTVKYTP RGAGSYTIMV 850
LFADQATPTS PIRVKVEPSH DASKVKAEGP GLSRTGVELG KPTHFTVNAK 900
AAGKGKLDVQ FSGLTKGDAV RDVDIIDHHD NTYTVKYTPV QQGPVGVNVT 950
YGGDPIPKSP FSVAVSPSLD LSKIKVSGLG EKVDVGKDQE FTVKSKGAGG 1000
QGKVASKIVG PSGAAVPCKV EPGLGADNSV VRFLPREEGP YEVEVTYDGV 1050
PVPGSPFPLE AVAPTKPSKV KAFGPGLQGG SAGSPARFTI DTKGAGTGGL 1100
GLTVEGPCEA QLECLDNGDG TCSVSYVPTE PGDYNINILF ADTHIPGSPF 1150
KAHVVPCFDA SKVKCSGPGL ERATAGEVGQ FQVDCSSAGS AELTIEICSE 1200
AGLPAEVYIQ DHGDGTHTIT YIPLCPGAYT VTIKYGGQPV PNFPSKLQVE 1250
PAVDTSGVQC YGPGIEGQGV FREATTEFSV DARALTQTGG PHVKARVANP 1300
SGNLTETYVQ DRGDGMYKVE YTPYEEGLHS VDVTYDGSPV PSSPFQVPVT 1350
EGCDPSRVRV HGPGIQSGTT NKPNKFTVET RGAGTGGLGL AVEGPSEAKM 1400
SCMDNKDGSC SVEYIPYEAG TYSLNVTYGG HQVPGSPFKV PVHDVTDASK 1450
VKCSGPGLSP GMVRANLPQS FQVDTSKAGV APLQVKVQGP KGLVEPVDVV 1500
DNADGTQTVN YVPSREGPYS ISVLYGDEEV PRSPFKVKVL PTHDASKVKA 1550
SGPGLNTTGV PASLPVEFTI DAKDAGEGLL AVQITDPEGK PKKTHIQDNH 1600
DGTYTVAYVP DVTGRYTILI KYGGDEIPFS PYRVRAVPTG DASKCTVTGA 1650
GIGPTIQIGE ETVITVDTKA AGKGKVTCTV CTPDGSEVDV DVVENEDGTF 1700
DIFYTAPQPG KYVICVRFGG EHVPNSPFQV TALAGDQPSV QPPLRSQQLA 1750
PQYTYAQGGQ QTWAPERPLV GVNGLDVTSL RPFDLVIPFT IKKGEITGEV 1800
RMPSGKVAQP TITDNKDGTV TVRYAPSEAG LHEMDIRYDN MHIPGSPLQF 1850
YVDYVNCGHV TAYGPGLTHG VVNKPATFTV NTKDAGEGGL SLAIEGPSKA 1900
EISCTDNQDG TCSVSYLPVL PGDYSILVKY NEQHVPGSPF TARVTGDDSM 1950
RMSHLKVGSA ADIPINISET DLSLLTATVV PPSGREEPCL LKRLRNGHVG 2000
ISFVPKETGE HLVHVKKNGQ HVASSPIPVV ISQSEIGDAS RVRVSGQGLH 2050
EGHTFEPAEF IIDTRDAGYG GLSLSIEGPS KVDINTEDLE DGTCRVTYCP 2100
TEPGNYIINI KFADQHVPGS PFSVKVTGEG RVKESITRRR RAPSVANVGS 2150
HCDLSLKIPE ISIQDMTAQV TSPSGKTHEA EIVEGENHTY CIRFVPAEMG 2200
THTVSVKYKG QHVPGSPFQF TVGPLGEGGA HKVRAGGPGL ERAEAGVPAE 2250
FSIWTREAGA GGLAIAVEGP SKAEISFEDR KDGSCGVAYV VQEPGDYEVS 2300
VKFNEEHIPD SPFVVPVASP SGDARRLTVS SLQESGLKVN QPASFAVSLN 2350
GAKGAIDAKV HSPSGALEEC YVTEIDQDKY AVRFIPRENG VYLIDVKFNG 2400
THIPGSPFKI RVGEPGHGGD PGLVSAYGAG LEGGVTGNPA EFVVNTSNAG 2450
AGALSVTIDG PSKVKMDCQE CPEGYRVTYT PMAPGSYLIS IKYGGPYHIG 2500
GSPFKAKVTG PRLVSNHSLH ETSSVFVDSL TKATCAPQHG APGPGPADAS 2550
KVVAKGLGLS KAYVGQKSSF TVDCSKAGNN MLLVGVHGPR TPCEEILVKH 2600
VGSRLYSVSY LLKDKGEYTL VVKWGDEHIP GSPYRVVVP

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