E2F1 is a predicted scaffold protein, which is related to the following pathway(s).

CDK2->CDK7->CDC2->HTATIP


E2F1 is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
BRCA1CDK2->CDK7->CDC2->E2F1
BRCA1CSNK2A1->CDC2->CDK7->E2F1
TP53BP1ATM->CHEK2->E2F1
MDM4ATM->CHEK2->E2F1


The sequence of E2F1

Amino acids in red are phosphorylation sites determined by MS/MS

MALAGAPAGG PCAPALEALL GAGALRLLDS SQIVIISAAQ DASAPPAPTG 50
PAAPAAGPCD PDLLLFATPQ APRPTPSAPR PALGRPPVKR RLDLETDHQY 100
LAESSGPARG RGRHPGKGVK SPGEKSRYET SLNLTTKRFL ELLSHSADGV 150
VDLNWAAEVL KVQKRRIYDI TNVLEGIQLI AKKSKNHIQW LGSHTTVGVG 200
GRLEGLTQDL RQLQESEQQL DHLMNICTTQ LRLLSEDTDS QRLAYVTCQD 250
LRSIADPAEQ MVMVIKAPPE TQLQAVDSSE NFQISLKSKQ GPIDVFLCPE 300
ETVGGISPGK TPSQEVTSEE ENRATDSATI VSPPPSSPPS SLTTDPSQSL 350
LSLEQEPLLS RMGSLRAPVD EDRLSPLVAA DSLLEHVRED FSGLLPEEFI 400
SLSPPHEALD YHFGLEEGEG IRDLFDCDFG DLTPLDF

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