CDC2 is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
PTPN1CDC2->CSNK2A1->AKT1
PTPN1CDC2->CSNK2A1->BCR
PTPN1CDC2->CSNK2A1->NFKBIA
PTPN1CSNK2A1->CDC2->EGFR->GRB2
PTPN1CSNK2A1->CDC2->EGFR->STAT5B
BRCA1CDK2->CDK7->CDC2->APLP2
BRCA1CDK2->CDK7->CDC2->CSNK2B
BRCA1CDK2->CDK7->CDC2->E2F1
BRCA1CDK2->CDK7->CDC2->FANCG
BRCA1CDK2->CDK7->CDC2->PPP1CA
BRCA1CSNK2A1->CDC2->CDK7->E2F1
BRCA1CSNK2A1->CDC2->CDK7->ESR1
BRCA1CSNK2A1->CDC2->CDK7->POU2F1
BRCA1CSNK2A1->CDC2->CDK7->TP53
BRCA1CDK2->CDK7->CDC2->CSNK2A1->AKT1
BRCA1CDK2->CDK7->CDC2->CSNK2A1->HDAC1
BRCA1CDK2->CDK7->CDC2->CSNK2A1->HDAC2
BRCA1CDK2->CDK7->CDC2->CSNK2A1->IFI16
BRCA1CDK2->CDK7->CDC2->CSNK2A1->JUN
BRCA1CDK2->CDK7->CDC2->CSNK2A1->RELA
BRCA1CDK2->CDK7->CDC2->CSNK2A1->XRCC1
BRCA1CSNK2A1->CDC2->CDK7->CDK4->RBL1
BRCA1CSNK2A1->CDC2->CDK7->CDK4->RBL2
BRCA1CSNK2A1->CDC2->CDK7->CDK4->SMAD3
PLEC1CDC2->EGFR->GRB2
PIN1PLK1->WEE1->CDC2->CDC25C
PIN1PLK1->WEE1->CDC2->CDC27
PIN1PLK1->WEE1->CDC2->PTPN1
PIN1PLK1->WEE1->CDC2->TOP2A
PIN1PLK1->WEE1->CDC2->CSNK2A1->JUN
PIN1PLK1->WEE1->CDC2->CSNK2A1->TOP2A
KRT18P19CDC2->EGFR->CBL
KRT18P19CDC2->EGFR->HGS
E2F1CDK2->CDK7->CDC2->HTATIP
PTPN2CDC2->EGFR->STAT1
PTPN2CDC2->EGFR->STAT5B
LY6G5BCDC2->CSNK2A1->CDC25B
LY6G5BCDC2->CSNK2A1->CDC34
LY6G5BCDC2->CSNK2A1->EIF5
LY6G5BCDC2->CSNK2A1->FAF1
LY6G5BCDC2->CSNK2A1->RNF7
LY6G5BLYN->CSNK2A1->CDC2->CDC25B
LZTS1CDC2->CDC25C
HMGA1CDC2->CSNK2A1->JUN
HMGA1CDC2->CSNK2A1->SRF
STMN1CDC2->CSNK2A1->CDKN1B
CREMCDC2->CSNK2A1->CDC34
INCENPCDC2->BIRC5
HMGA2CDC2->CSNK2A1->RELA
WEE1CDC2->CSNK2A1->ARRB2
ERCC2CDC2->CDK7->TP53
RPS6KB1CDC2->CSNK2A1->AKT1
RPS6KB1CDC2->CSNK2A1->MAPK9
RPS6KB1LYN->CSNK2A1->CDC2->CSNK2B


The sequence of CDC2

Amino acids in red are phosphorylation sites determined by MS/MS

MEDYTKIEKI GEGTYGVVYK GRHKTTGQVV AMKKIRLESE EEGVPSTAIR 50
EISLLKELRH PNIVSLQDVL MQDSRLYLIF EFLSMDLKKY LDSIPPGQYM 100
DSSLVKSYLY QILQGIVFCH SRRVLHRDLK PQNLLIDDKG TIKLADFGLA 150
RAFGIPIRVY THEVVTLWYR SPEVLLGSAR YSTPVDIWSI GTIFAELATK 200
KPLFHGDSEI DQLFRIFRAL GTPNNEVWPE VESLQDYKNT FPKWKPGSLA 250
SHVKNLDENG LDLLSKMLIY DPAKRISGKM ALNHPYFNDL DNQIKKM 300

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