| CSK | -> | FYN | -> | CTNNB1 | CSK | -> | SRC | -> | BMX | CSK | -> | SRC | -> | CAV2 | CSK | -> | SRC | -> | CTNNB1 | CSK | -> | SRC | -> | DAG1 | CSK | -> | SRC | -> | ESR1 | CSK | -> | SRC | -> | LRP1 | CSK | -> | SRC | -> | PTPN6 | MAPK1 | -> | EGFR | -> | PTPN1 | MAPK3 | -> | EGFR | -> | PTPN1 | PDGFRA | -> | SRC | -> | BMX | PDGFRA | -> | SRC | -> | CAV2 | PDGFRA | -> | SRC | -> | CTNNB1 | PDGFRA | -> | SRC | -> | DAG1 | PDGFRA | -> | SRC | -> | ESR1 | PDGFRA | -> | SRC | -> | LRP1 | PDGFRA | -> | SRC | -> | PTPN6 | CSK | -> | SRC | -> | EGFR | -> | PTPN1 | PDGFRA | -> | SRC | -> | EGFR | -> | PTPN1 | CSK | -> | SRC | -> | ABL1 | -> | BTK | -> | BMX | PDGFRA | -> | SRC | -> | ABL1 | -> | BTK | -> | BMX |
CAV1 is a known scaffold protein, which is related to the following pathway(s).
| GNAI1 | -> | HRAS | -> | SRC |
Reference:Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases.
PMID:8910575
| Scaffold Protein(s) | Related Pathway(s) | PTPN1 | SRC->CAV1 | PLD2 | CSK->FYN->CAV1 | PLD2 | CSK->SRC->CAV1 | GJA1 | CSK->SRC->CAV1 | PTPN11 | PDGFRA->SRC->CAV1 | PTPN11 | PDGFRB->FYN->CAV1 | DNM1 | CDK5->SRC->CAV1 | SRC | SYK->PRKCA->ADRBK1->PDGFRB->FYN->CAV1 | INSR | CSK->SRC->CAV1 | DAG1 | CSK->FYN->CAV1 | DAG1 | CSK->SRC->CAV1 |
|---|
CAV1 is also a known signal protein, which is involved in the following pathway(s)
| Scaffold Protein(s) | Related Pathway(s) | PMID |
|---|---|---|
| STRN | ->CAV1->STRN4 | 11707266 |
Reference:Striatin, a calmodulin-dependent scaffolding protein, directly binds caveolin-1.
PMID:11707266
The sequence of CAV1
Amino acids in red are phosphorylation sites determined by MS/MS
MSGGKYVDSE GHLYTVPIRE QGNIYKPNNK AMADELSEKQ VYDAHTKEID 50
LVNRDPKHLN DDVVKIDFED VIAEPEGTHS FDGIWKASFT TFTVTKYWFY 100
RLLSALFGIP MALIWGIYFA ILSFLHIWAV VPCIKSFLIE IQCISRVYSI 150
YVHTVCDPLF EAVGKIFSNV RINLQKEI