ABL1 is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
INPPL1SRC->ABL1->CBL
GRB10SRC->ABL1->BCR
PTPN18CSK->SRC->ABL1->PSTPIP1
ARHGAP17SRC->ABL1->BTK
ARHGAP17SRC->ABL1->CRK
SHC1CSK->SRC->ABL1->BCR
SHC1CSK->SRC->ABL1->CBL
SHC1CSK->SRC->ABL1->CRKL
SHC1CSK->SRC->ABL1->PLSCR1
SH3BP2ABL1->CBL
PLCG1PDGFRA->SRC->ABL1->BCR
PLCG1PDGFRA->SRC->ABL1->CBL
PLCG1PDGFRA->SRC->ABL1->PRKD1
PLCG1PDGFRA->SRC->ABL1->BTK->TEC
PLCG1PDGFRA->SRC->ABL1->BTK->WAS
PLCG1PDGFRA->SRC->ABL1->BTK->ITK->CD28
PLCG1PDGFRA->SRC->ABL1->BTK->ITK->TEC
CBLCSK->SRC->ABL1->BCR
CBLCSK->SRC->ABL1->CRKL
CBLPDGFRA->SRC->ABL1->BCR
CBLPDGFRA->SRC->ABL1->CRK
CBLPDGFRA->SRC->ABL1->CRKL
CBLCSK->SRC->ABL1->BTK->ITK
CBLPDGFRA->SRC->ABL1->BTK->ITK
DOK1CSK->SRC->ABL1->CRKL
GRB2PDGFRA->SRC->ABL1->BCR
GRB2PDGFRA->SRC->ABL1->CBL
GRB2PDGFRA->SRC->ABL1->CRK
GRB2PDGFRA->SRC->ABL1->CRKL
GRB2PDGFRA->SRC->ABL1->MUC1
GRB2PDGFRA->SRC->ABL1->WASF2
PRKD1SRC->ABL1->BTK->PLCG2
CAV1CSK->SRC->ABL1->BTK->BMX
CAV1PDGFRA->SRC->ABL1->BTK->BMX
CD19ABL1->BTK->PLCG2
PTPN6SRC->ABL1->BCR
PTPN6SRC->ABL1->CBL
PXNCSK->SRC->ABL1->BCR
PXNCSK->SRC->ABL1->CBL
PXNCSK->SRC->ABL1->CRKL
CRKPDGFRA->SRC->ABL1->CBL
CRKPDGFRA->SRC->ABL1->CRKL
CRKPDGFRA->SRC->ABL1->PLSCR1
RASA1CSK->SRC->ABL1->BCR
SH3BP1SRC->ABL1->CRK
KITSRC->ABL1->BCR
KITSRC->ABL1->CBL
KITSRC->ABL1->CRK
KITSRC->ABL1->CRKL
KITSRC->ABL1->BTK->TEC
PIK3R1PDGFRA->SRC->ABL1->CBL
PIK3R1PDGFRA->SRC->ABL1->CRK
PIK3R1PDGFRA->SRC->ABL1->CRKL
PIK3R1PDGFRA->SRC->ABL1->NFKBIA
BCAR1SRC->ABL1->CRK
BCAR1SRC->ABL1->CRKL
CABLES2ABL1->CDK5
MAP4K5ABL1->BCR
MAP4K5ABL1->CRK
MAP4K5ABL1->CRKL
EVLSRC->ABL1->CRKL



ABL1 is a known signal protein, which is involved in the following pathway(s)

Scaffold Protein(s)Related Pathway(s)PMID
WASF1PKA->ABL110970852

Reference: Scar/WAVE-1, a Wiskott-Aldrich syndrome protein, assembles an actin-associated multi-kinase scaffold.

PMID:10970852


The sequence of ABL1

Amino acids in red are phosphorylation sites determined by MS/MS

MGQQPGKVLG DQRRPSLPAL HFIKGAGKKE SSRHGGPHCN VFVEHEALQR 50
PVASDFEPQG LSEAARWNSK ENLLAGPSEN DPNLFVALYD FVASGDNTLS 100
ITKGEKLRVL GYNHNGEWCE AQTKNGQGWV PSNYITPVNS LEKHSWYHGP 150
VSRNAAEYLL SSGINGSFLV RESESSPGQR SISLRYEGRV YHYRINTASD 200
GKLYVSSESR FNTLAELVHH HSTVADGLIT TLHYPAPKRN KPTVYGVSPN 250
YDKWEMERTD ITMKHKLGGG QYGEVYEGVW KKYSLTVAVK TLKEDTMEVE 300
EFLKEAAVMK EIKHPNLVQL LGVCTREPPF YIITEFMTYG NLLDYLRECN 350
RQEVNAVVLL YMATQISSAM EYLEKKNFIH RDLAARNCLV GENHLVKVAD 400
FGLSRLMTGD TYTAHAGAKF PIKWTAPESL AYNKFSIKSD VWAFGVLLWE 450
IATYGMSPYP GIDLSQVYEL LEKDYRMERP EGCPEKVYEL MRACWQWNPS 500
DRPSFAEIHQ AFETMFQESS ISDEVEKELG KQGVRGAVST LLQAPELPTK 550
TRTSRRAAEH RDTTDVPEMP HSKGQGESDP LDHEPAVSPL LPRKERGPPE 600
GGLNEDERLL PKDKKTNLFS ALIKKKKKTA PTPPKRSSSF REMDGQPERR 650
GAGEEEGRDI SNGALAFTPL DTADPAKSPK PSNGAGVPNG ALRESGGSGF 700
RSPHLWKKSS TLTSSRLATG EEEGGGSSSK RFLRSCSASC VPHGAKDTEW 750
RSVTLPRDLQ STGRQFDSST FGGHKSEKPA LPRKRAGENR SDQVTRGTVT 800
PPPRLVKKNE EAADEVFKDI MESSPGSSPP NLTPKPLRRQ VTVAPASGLP 850
HKEEAGKGSA LGTPAAAEPV TPTSKAGSGA PGGTSKGPAE ESRVRRHKHS 900
SESPGRDKGK LSRLKPAPPP PPAASAGKAG GKPSQSPSQE AAGEAVLGAK 950
TKATSLVDAV NSDAAKPSQP GEGLKKPVLP ATPKPQSAKP SGTPISPAPV 1000
PSTLPSASSA LAGDQPSSTA FIPLISTRVS LRKTRQPPER IASGAITKGV 1050
VLDSTEALCL AISRNSEQMA SHSAVLEAGK NLYTFCVSYV DSIQQMRNKF 1100
AFREAINKLE NNLRELQICP ATAGSGPAAT QDFSKLLSSV KEISDIVQR 1150

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