WEE1 is a predicted scaffold protein, which is related to the following pathway(s).

CDC2->CSNK2A1->ARRB2


WEE1 is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
PIN1PLK1->WEE1->CDC2->CDC25C
PIN1PLK1->WEE1->CDC2->CDC27
PIN1PLK1->WEE1->CDC2->PTPN1
PIN1PLK1->WEE1->CDC2->TOP2A
PIN1PLK1->WEE1->CDC2->CSNK2A1->JUN
PIN1PLK1->WEE1->CDC2->CSNK2A1->TOP2A


The sequence of WEE1

Amino acids in red are phosphorylation sites determined by MS/MS

MSFLSRQQPP PPRRAGAACT LRQKLIFSPC SDCEEEEEEE EEEGSGHSTG 50
EDSAFQEPDS PLPPARSPTE PGPERRRSPG PAPGSPGELE EDLLLPGACP 100
GADEAGGGAE GDSWEEEGFG SSSPVKSPAA PYFLGSSFSP VRCGGPGDAS 150
PRGCGARRAG EGRRSPRPDH PGTPPHKTFR KLRLFDTPHT PKSLLSKARG 200
IDSSSVKLRG SSLFMDTEKS GKREFDVRQT PQVNINPFTP DSLLLHSSGQ 250
CRRRKRTYWN DSCGEDMEAS DYELEDETRP AKRITITESN MKSRYTTEFH 300
ELEKIGSGEF GSVFKCVKRL DGCIYAIKRS KKPLAGSVDE QNALREVYAH 350
AVLGQHSHVV RYFSAWAEDD HMLIQNEYRN GGSLADAISE NYRIMSYFKE 400
AELKDLLLQV GRGLRYIHSM SLVHMDIKPS NIFISRTSIP NAASEEGDED 450
DWASNKVMFK IGDLGHVTRI SSPQVEEGDS RFLANEVLQE NYTHLPKADI 500
FALALTVVCA AGAEPLPRNG DQWHEIRQGR LPRIPQVLSQ EFTELLKVMI 550
HPDPERRPSA MALVKHSVLL SASRKSAEQL RIELNAEKFK NSLLQKELKK 600
AQMAKAAAEE RALFTDRMAT RSTTQSNRTS RLIGKKMNRS VSLTIY 650

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