| Scaffold Protein(s) | Related Pathway(s) | SH3BP2 | LCK->VAV2 | CBL | CSK->SRC->EGFR->VAV2 | CBL | PDGFRA->SRC->EGFR->VAV2 | CBL | SYK->PRKCA->EGFR->VAV2 | GRB2 | PDGFRA->SRC->EGFR->VAV2 | PDGFRB | PDGFRA->SRC->EGFR->VAV2 |
|---|
The sequence of VAV2
Amino acids in red are phosphorylation sites determined by MS/MS
MEQWRQCGRW LIDCKVLPPN HRVVWPSAVV FDLAQALRDG VLLCQLLHNL 50
SPGSIDLKDI NFRPQMSQFL CLKNIRTFLK VCHDKFGLRN SELFDPFDLF 100
DVRDFGKVIS AVSRLSLHSI AQNKGIRPFP SEETTENDDD VYRSLEELAD 150
EHDLGEDIYD CVPCEDGGDD IYEDIIKVEV QQPMKMGMTE DDKRNCCLLE 200
IQETEAKYYR TLEDIEKNYM SPLRLVLSPA DMAAVFINLE DLIKVHHSFL 250
RAIDVSVMVG GSTLAKVFLD FKERLLIYGE YCSHMEHAQN TLNQLLASRE 300
DFRQKVEECT LKVQDGKFKL QDLLVVPMQR VLKYHLLLKE LLSHSAERPE 350
RQQLKEALEA MQDLAMYINE VKRDKETLRK ISEFQSSIEN LQVKLEEFGR 400
PKIDGELKVR SIVNHTKQDR YLFLFDKVVI VCKRKGYSYE LKEIIELLFH 450
KMTDDPMNNK DVKKWSYGFY LIHLQGKQGF QFFCKTEDMK RKWMEQFEMA 500
MSNIKPDKAN ANHHSFQMYT FDKTTNCKAC KMFLRGTFYQ GYMCTKCGVG 550
AHKECLEVIP PCKFTSPADL DASGAGPGPK MVAMQNYHGN PAPPGKPVLT 600
FQTGDVLELL RGDPESPWWE GRLVQTRKSG YFPSSSVKPC PVDGRPPISR 650
PPSREIDYTA YPWFAGNMER QQTDNLLKSH ASGTYLIRER PAEAERFAIS 700
IKFNDEVKHI KVVEKDNWIH ITEAKKFDSL LELVEYYQCH SLKESFKQLD 750
TTLKYPYKSR ERSASRASSR SPVFTPRVIG TAVARYNFAA RDMRELSLRE 800
GDVVRIYSRI GGDQGWWKGE TNGRIGWFPS TYVEEEGIQ