TRAF6 is a known signal protein, which is involved in the following pathway(s)
TRAF6 is a known signal protein, which is involved in the following pathway(s)
| Scaffold Protein(s) | Related Pathway(s) | PMID |
|---|---|---|
| PELI1 | IRAK1->TRAF6 | 16951688 |
| SQSTM1 | PRKCI->ERK->RIP1->TRAF6 | 17174552 |
Reference:Smad6 negatively regulates interleukin 1-receptor-Toll-like receptor signaling through direct interaction with the adaptor Pellino-1.
PMID:16951688
Reference:Signal integration and diversification through the p62 scaffold protein.
PMID:17174552
The sequence of TRAF6
Amino acids in red are phosphorylation sites determined by MS/MS
MSLLNCENSC GFSQSESDCC VAMASSCSAV TKDDSVGGTA STGNLSSSFM 50
EEIQGYDVEF DPPLESKYEC PICLMALREA VQTPCGHRFC KACIIKSIRD 100
AGHKCPVDNE ILLENQLFPD NFAKREILSL MVKCPNEGCL HKMELRHLED 150
HQAHCEFALM DCPQCQRPFQ KFHINIHILK DCPRRQVSCD NCAASMAFED 200
KEIHDQNCPL ANVICEYCNT ILIREQMPNH YDLDCPTAPI PCTFSTFGCH 250
EKMQRNHLAR HLQENTQSHM RMLAQAVHSL SVIPDSGYIS EVRNFQETIH 300
QLEGRLVRQD HQIRELTAKM ETQSMYVSEL KRTIRTLEDK VAEIEAQQCN 350
GIYIWKIGNF GMHLKCQEEE KPVVIHSPGF YTGKPGYKLC MRLHLQLPTA 400
QRCANYISLF VHTMQGEYDS HLPWPFQGTI RLTILDQSEA PVRQNHEEIM 450
DAKPELLAFQ RPTIPRNPKG FGYVTFMHLE ALRQRTFIKD DTLLVRCEVS 500
TRFDMGSLRR EGFQPRSTDA GV