TEC is a predicted scaffold protein, which is related to the following pathway(s).

LYN->BTK->BMX
LYN->BTK->PLCG2
LYN->BTK->WAS


TEC is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
PLCG2LCK->ITK->TEC
PLCG2LYN->BTK->TEC
PLCG2LYN->BTK->ITK->TEC
PLCG1LCK->ITK->TEC
PLCG1LYN->BTK->TEC
PLCG1LYN->BTK->ITK->TEC
PLCG1PDGFRA->SRC->ABL1->BTK->TEC
PLCG1PDGFRA->SRC->ABL1->BTK->ITK->TEC
PTPN21TEC->BMX
PIP5K2ABTK->TEC
BTKITK->TEC->BMX
KITLYN->BTK->TEC
KITSRC->ABL1->BTK->TEC
BMXBTK->ITK->TEC
WASBTK->ITK->TEC


The sequence of TEC

Amino acids in red are phosphorylation sites determined by MS/MS

MNFNTILEEI LIKRSQQKKK TSPLNYKERL FVLTKSMLTY YEGRAEKKYR 50
KGFIDVSKIK CVEIVKNDDG VIPCQNKYPF QVVHDANTLY IFAPSPQSRD 100
LWVKKLKEEI KNNNNIMIKY HPKFWTDGSY QCCRQTEKLA PGCEKYNLFE 150
SSIRKALPPA PETKKRRPPP PIPLEEEDNS EEIVVAMYDF QAAEGHDLRL 200
ERGQEYLILE KNDVHWWRAR DKYGNEGYIP SNYVTGKKSN NLDQYEWYCR 250
NMNRSKAEQL LRSEDKEGGF MVRDSSQPGL YTVSLYTKFG GEGSSGFRHY 300
HIKETTTSPK KYYLAEKHAF GSIPEIIEYH KHNAAGLVTR LRYPVSVKGK 350
NAPTTAGFSY EKWEINPSEL TFMRELGSGL FGVVRLGKWR AQYKVAIKAI 400
REGAMCEEDF IEEAKVMMKL THPKLVQLYG VCTQQKPIYI VTEFMERGCL 450
LNFLRQRQGH FSRDVLLSMC QDVCEGMEYL ERNSFIHRDL AARNCLVSEA 500
GVVKVSDFGM ARYVLDDQYT SSSGAKFPVK WCPPEVFNYS RFSSKSDVWS 550
FGVLMWEVFT EGRMPFEKYT NYEVVTMVTR GHRLYQPKLA SNYVYEVMLR 600
CWQEKPEGRP SFEDLLRTID ELVECEETFG R

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