STAT1 is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
CXCR4JAK3->JAK1->STAT1
DUSP3MAPK1->EGFR->STAT1
DUSP3MAP2K2->MAPK3->EGFR->STAT1
PTPN11MAPK3->EGFR->STAT1
PTPN11PDGFRA->SRC->STAT1
PTPN11PRKCA->EGFR->STAT1
PTPN11PDGFRA->SRC->EGFR->STAT1
PTK2CSK->SRC->STAT1
PTK2CSK->SRC->EGFR->STAT1
STAT5BJAK3->JAK1->STAT1
STAT5BMAPK1->EGFR->STAT1
STAT5BPDGFRA->SRC->STAT1
STAT5BPDGFRA->SRC->EGFR->STAT1
STAT5AJAK3->JAK1->STAT1
STAT5AMAPK1->EGFR->STAT1
STAT5AMAPK3->EGFR->STAT1
STAT5APDGFRA->SRC->STAT1
STAT5APDGFRA->SRC->EGFR->STAT1
PTPN2CDC2->EGFR->STAT1
PTPN2CDK5->SRC->STAT1
PTPN2JAK3->JAK1->STAT1
PTPN2CDK5->SRC->EGFR->STAT1
MAPK14MAP2K1->MAPK1->EGFR->STAT1
MAPK14MAPK1->MAP2K1->MAPK3->EGFR->STAT1
PDGFRBPDGFRA->SRC->STAT1
PDGFRBPDGFRA->SRC->EGFR->STAT1
STATIP1JAK1->STAT1
STATIP1JAK2->STAT1
IL2RBJAK3->JAK1->STAT1
IL2RGJAK3->JAK1->STAT1



STAT1 is a known signal protein, which is involved in the following pathway(s)

Scaffold Protein(s)Related Pathway(s)PMID
JAK2AT1R->STAT112386143

Reference:Regulation of G protein-coupled receptor signaling by scaffold proteins.

PMID:12386143


The sequence of STAT1

Amino acids in red are phosphorylation sites determined by MS/MS

MSQWYELQQL DSKFLEQVHQ LYDDSFPMEI RQYLAQWLEK QDWEHAANDV 50
SFATIRFHDL LSQLDDQYSR FSLENNFLLQ HNIRKSKRNL QDNFQEDPIQ 100
MSMIIYSCLK EERKILENAQ RFNQAQSGNI QSTVMLDKQK ELDSKVRNVK 150
DKVMCIEHEI KSLEDLQDEY DFKCKTLQNR EHETNGVAKS DQKQEQLLLK 200
KMYLMLDNKR KEVVHKIIEL LNVTELTQNA LINDELVEWK RRQQSACIGG 250
PPNACLDQLQ NWFTIVAESL QQVRQQLKKL EELEQKYTYE HDPITKNKQV 300
LWDRTFSLFQ QLIQSSFVVE RQPCMPTHPQ RPLVLKTGVQ FTVKLRLLVK 350
LQELNYNLKV KVLFDKDVNE RNTVKGFRKF NILGTHTKVM NMEESTNGSL 400
AAEFRHLQLK EQKNAGTRTN EGPLIVTEEL HSLSFETQLC QPGLVIDLET 450
TSLPVVVISN VSQLPSGWAS ILWYNMLVAE PRNLSFFLTP PCARWAQLSE 500
VLSWQFSSVT KRGLNVDQLN MLGEKLLGPN ASPDGLIPWT RFCKENINDK 550
NFPFWLWIES ILELIKKHLL PLWNDGCIMG FISKERERAL LKDQQPGTFL 600
LRFSESSREG AITFTWVERS QNGGEPDFHA VEPYTKKELS AVTFPDIIRN 650
YKVMAAENIP ENPLKYLYPN IDKDHAFGKY YSRPKEAPEP MELDGPKGTG 700
YIKTELISVS EV

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