SMAD1 is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
PAK1RAF1->MAP2K1->MAPK1->SMAD1
FBXL12TGFBR1->SMAD1
VEPH1BMPR1B->SMAD1
VEPH1TGFBR1->SMAD1
PREBTGFBR1->SMAD1
RASL12BMPR1B->SMAD1
RASL12TGFBR1->SMAD1
GDF6BMPR1B->SMAD1
PLEKHB1BMPR1B->SMAD1
PLEKHB1TGFBR1->SMAD1
RAB34TGFBR1->SMAD1
EIF2AK4TGFBR1->SMAD1
RAB38BMPR1B->SMAD1
RAB38TGFBR1->SMAD1
USP45BMPR1B->SMAD1
USP45TGFBR1->SMAD1


The sequence of SMAD1

Amino acids in red are phosphorylation sites determined by MS/MS

MNVTSLFSFT SPAVKRLLGW KQGDEEEKWA EKAVDALVKK LKKKKGAMEE 50
LEKALSCPGQ PSNCVTIPRS LDGRLQVSHR KGLPHVIYCR VWRWPDLQSH 100
HELKPLECCE FPFGSKQKEV CINPYHYKRV ESPVLPPVLV PRHSEYNPQH 150
SLLAQFRNLG QNEPHMPLNA TFPDSFQQPN SHPFPHSPNS SYPNSPGSSS 200
STYPHSPTSS DPGSPFQMPA DTPPPAYLPP EDPMTQDGSQ PMDTNMMAPP 250
LPSEINRGDV QAVAYEEPKH WCSIVYYELN NRVGEAFHAS STSVLVDGFT 300
DPSNNKNRFC LGLLSNVNRN STIENTRRHI GKGVHLYYVG GEVYAECLSD 350
SSIFVQSRNC NYHHGFHPTT VCKIPSGCSL KIFNNQEFAQ LLAQSVNHGF 400
ETVYELTKMC TIRMSFVKGW GAEYHRQDVT STPCWIEIHL HGPLQWLDKV 450
LTQMGSPHNP ISSVS

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