SHC is a known signal protein, which is involved in the following pathway(s)

Scaffold Protein(s)	Related Pathway(s)	PMID
GRB2	PTPN12->SHC->SHIP	11432829
IRS1	GRB2->SHC	The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc
PTPN12	SHC->SHIP->GRB2	11432829

Reference:PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates.

PMID:11432829

Reference: implications for insulin control of ras signalling.

PMID:The SH2/SH3 domain-containing protein GRB2 interacts with tyrosine-phosphorylated IRS1 and Shc

Reference:PTP-PEST, a scaffold protein tyrosine phosphatase, negatively regulates lymphocyte activation by targeting a unique set of substrates.

PMID:11432829

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