SH3BP2 is a predicted scaffold protein, which is related to the following pathway(s).

ABL1->CBL
FGFR1->PLCG1
FYN->CBL
FYN->PLCG2
LCK->CBL
LCK->PLCG2
LCK->VAV1
LCK->VAV2
LCK->ZAP70
SYK->CBL
SYK->PLCG1


SH3BP2 is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
CBLSYK->PRKCA->SH3BP2


The sequence of SH3BP2

Amino acids in red are phosphorylation sites determined by MS/MS

MAAEEMHWPV PMKAIGAQNL LTMPGGVAKA GYLHKKGGTQ LQLLKWPLRF 50
VIIHKRCVYY FKSSTSASPQ GAFSLSGYNR VMRAAEETTS NNVFPFKIIH 100
ISKKHRTWFF SASSEEERKS WMALLRREIG HFHEKKDLPL DTSDSSSDTD 150
SFYGAVERPV DISLSPYPTD NEDYEHDDED DSYLEPDSPE PGRLEDALMH 200
PPAYPPPPVP TPRKPAFSDM PRAHSFTSKG PGPLLPPPPP KHGLPDVGLA 250
AEDSKRDPLC PRRAEPCPRV PATPRRMSDP PLSTMPTAPG LRKPPCFRES 300
ASPSPEPWTP GHGACSTSSA AIMATATSRN CDKLKSFHLS PRGPPTSEPP 350
PVPANKPKFL KIAEEDPPRE AAMPGLFVPP VAPRPPALKL PVPEAMARPA 400
VLPRPEKPQL PHLQRSPLDG QSFRSFSFEK PRQPSQADTG GDDSDEDYEK 450
VPLPNSVFVN TTESCEVERL FKATSPRGEP QDGLYCIRNS STKSGKVLVV 500
WDETSNKVRN YRIFEKDSKF YLEGEVLFVS VGSMVEHYHT HVLPSHQSLL 550
LRHPYGYTGP R

Home