RASA1 is a predicted scaffold protein, which is related to the following pathway(s).

CSK->SRC->CAV2
CSK->SRC->GNB2L1
CSK->SRC->GRLF1
CSK->SRC->IGF1R
CSK->SRC->KIT
CSK->SRC->PIK3R1
CSK->SRC->PXN
CSK->SRC->SHC1
LCK->ZAP70->SHC1
CSK->SRC->ABL1->BCR
CSK->SRC->EGFR->GRB2
CSK->SRC->EGFR->PLCG1


RASA1 is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
SHC1MAPK1->EGFR->RASA1
SHC1CSK->SRC->EGFR->RASA1
SHC1SYK->PRKCA->EGFR->RASA1
LYNCSK->SRC->EGFR->RASA1
PLCG1PDGFRA->SRC->EGFR->RASA1
GRB2PDGFRA->SRC->EGFR->RASA1
IGF1RCSK->SRC->EGFR->RASA1
PDGFRBPDGFRA->SRC->EGFR->RASA1
CSKSRC->EGFR->RASA1
PXNCSK->SRC->EGFR->RASA1
PIK3R1PDGFRA->SRC->EGFR->RASA1
CAV2SRC->EGFR->RASA1


The sequence of RASA1

Amino acids in red are phosphorylation sites determined by MS/MS

MMAAEAGSEE GGPVTAGAGG GGAAAGSSAY PAVCRVKIPA ALPVAAAPYP 50
GLVETGVAGT LGGGAALGSE FLGAGSVAGA LGGAGLTGGG TAAGVAGAAA 100
GVAGAAVAGP SGDMALTKLP TSLLAETLGP GGGFPPLPPP PYLPPLGAGL 150
GTVDEGDSLD GPEYEEEEVA IPLTAPPTNQ WYHGKLDRTI AEERLRQAGK 200
SGSYLIRESD RRPGSFVLSF LSQMNVVNHF RIIAMCGDYY IGGRRFSSLS 250
DLIGYYSHVS CLLKGEKLLY PVAPPEPVED RRRVRAILPY TKVPDTDEIS 300
FLKGDMFIVH NELEDGWMWV TNLRTDEQGL IVEDLVEEVG REEDPHEGKI 350
WFHGKISKQE AYNLLMTVGQ VCSFLVRPSD NTPGDYSLYF RTNENIQRFK 400
ICPTPNNQFM MGGRYYNSIG DIIDHYRKEQ IVEGYYLKEP VPMQDQEQVL 450
NDTVDGKEIY NTIRRKTKDA FYKNIVKKGY LLKKGKGKRW KNLYFILEGS 500
DAQLIYFESE KRATKPKGLI DLSVCSVYVV HDSLFGRPNC FQIVVQHFSE 550
EHYIFYFAGE TPEQAEDWMK GLQAFCNLRK SSPGTSNKRL RQVSSLVLHI 600
EEAHKLPVKH FTNPYCNIYL NSVQVAKTHA REGQNPVWSE EFVFDDLPPD 650
INRFEITLSN KTKKSKDPDI LFMRCQLSRL QKGHATDEWF LLSSHIPLKG 700
IEPGSLRVRA RYSMEKIMPE EEYSEFKELI LQKELHVVYA LSHVCGQDRT 750
LLASILLRIF LHEKLESLLL CTLNDREISM EDEATTLFRA TTLASTLMEQ 800
YMKATATQFV HHALKDSILK IMESKQSCEL SPSKLEKNED VNTNLTHLLN 850
ILSELVEKIF MASEILPPTL RYIYGCLQKS VQHKWPTNTT MRTRVVSGFV 900
FLRLICPAIL NPRMFNIISD SPSPIAARTL ILVAKSVQNL ANLVEFGAKE 950
PYMEGVNPFI KSNKHRMIMF LDELGNVPEL PDTTEHSRTD LSRDLAALHE 1000
ICVAHSDELR TLSNERGAQQ HVLKKLLAIT ELLQQKQNQY TKTNDVR 1050

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