RAPGEF1 is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
SHC1CSK->SRC->RAPGEF1
CRKPDGFRA->SRC->RAPGEF1


The sequence of RAPGEF1

Amino acids in red are phosphorylation sites determined by MS/MS

MGNAIEKQKP LKRSHLYPWK QDSQRSHLSS FTMKLMDKFH SPKIKRTPSK 50
KGKPAEVSVK IPEKPVNKEA TDRFLPEGYP LPLDLEQQAV EFMSTSAVAS 100
RSQRQKNLSW LEEKEKEVVS ALRYFKTIVD KMAIDKKVLE MLPGSASKVL 150
EAILPLVQND PRIQHSSALS SCYSRVYQSL ANLIRWSDQV MLEGVNSEDK 200
EMVTTVKGVI KAVLDGVKEL VRLTIEKQGR PSPTSPVKPS SPASKPDGPA 250
ELPLTDREVE ILNKTTGMSQ STELLPDATD EEVAPPKPPL PGIRVVDNSP 300
PPALPPKKRQ SAPSPTRVAV VAPMSRATSG SSLPVGINRQ DFDVDCYAQR 350
RLSGGSHSYG GESPRLSPCS SIGKLSKSDE QLSSLDRDSG QCSRNTSCET 400
LDHYDPDYEF LQQDLSNADQ IPQQTAWNLS PLPESLGESG SPFLGPPFQL 450
PLGGHPQPDG PLAPGQQTDT PPALPEKKRR SAASQTADGS GCRVSYERHP 500
SQYDNISGED LQSTAPIPSV PYAPFAAILP FQHGGSSAPV EFVGDFTAPE 550
STGDPEKPPP LPEKKNKHML AYMQLLEDYS EPQPSMFYQT PQNEHIYQQK 600
NKLLMEVYGF SDSFSGVDSV QELAPPPALP PKQRQLEPPA GKDGHPRDPS 650
AVSGVPGKDS RDGSERAPKS PDALESAQSE EEVDELSLID HNEIMSRLTL 700
KQEGDDGPDV RGGSGDILLV HATETDRKDL VLYCEAFLTT YRTFISPEEL 750
IKKLQYRYEK FSPFADTFKK RVSKNTFFVL VRVVDELCLV ELTEEILKLL 800
MELVFRLVCN GELSLARVLR KNILDKVDQK KLLRCATSSQ PLAARGVAAR 850
PGTLHDFHSH EIAEQLTLLD AELFYKIEIP EVLLWAKEQN EEKSPNLTQF 900
TEHFNNMSYW VRSIIMLQEK AQDRERLLLK FIKIMKHLRK LNNFNSYLAI 950
LSALDSAPIR RLEWQKQTSE GLAEYCTLID SSSSFRAYRA ALSEVEPPCI 1000
PYLGLILQDL TFVHLGNPDY IDGKVNFSKR WQQFNILDSM RCFQQAHYDM 1050
RRNDDIINFF NDFSDHLAEE ALWELSLKIK PRNITRRKTD REEKT 1100

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