PRKCZ is a predicted scaffold protein, which is related to the following pathway(s).

MAPK1->MAP2K1->GSK3B->PSEN1
MAPK1->MAP2K1->GSK3B->RELA
MAPK1->MAP2K1->MAPK3->CASP9
MAPK1->MAP2K1->MAPK3->IRS1
MAPK1->MAP2K1->MAPK3->MBP
MAPK1->MAP2K1->MAPK3->GSK3B->PSEN1
MAPK1->MAP2K1->MAPK3->GSK3B->RELA
SRC->RAF1->MAP2K1->GSK3B->PSEN1
SRC->RAF1->MAP2K1->GSK3B->RELA
SRC->RAF1->MAP2K1->MAPK1->CASP9
SRC->RAF1->MAP2K1->MAPK1->MBP
SRC->RAF1->MAP2K1->MAPK1->RELA
SRC->RAF1->MAP2K1->MAPK3->CASP9
SRC->RAF1->MAP2K1->MAPK3->IRS1
SRC->RAF1->MAP2K1->MAPK3->MBP
SRC->RAF1->MAP2K1->MAPK1->GSK3B->PSEN1
SRC->RAF1->MAP2K1->MAPK1->GSK3B->RELA
SRC->RAF1->MAP2K1->MAPK3->GSK3B->PSEN1
SRC->RAF1->MAP2K1->MAPK3->GSK3B->RELA


The sequence of PRKCZ

Amino acids in red are phosphorylation sites determined by MS/MS

MPSRTGPKME GSGGRVRLKA HYGGDIFITS VDAATTFEEL CEEVRDMCRL 50
HQQHPLTLKW VDSEGDPCTV SSQMELEEAF RLARQCRDEG LIIHVFPSTP 100
EQPGLPCPGE DKSIYRRGAR RWRKLYRANG HLFQAKRFNR RAYCGQCSER 150
IWGLARQGYR CINCKLLVHK RCHGLVPLTC RKHMDSVMPS QEPPVDDKNE 200
DADLPSEETD GIAYISSSRK HDSIKDDSED LKPVIDGMDG IKISQGLGLQ 250
DFDLIRVIGR GSYAKVLLVR LKKNDQIYAM KVVKKELVHD DEDIDWVQTE 300
KHVFEQASSN PFLVGLHSCF QTTSRLFLVI EYVNGGDLMF HMQRQRKLPE 350
EHARFYAAEI CIALNFLHER GIIYRDLKLD NVLLDADGHI KLTDYGMCKE 400
GLGPGDTTST FCGTPNYIAP EILRGEEYGF SVDWWALGVL MFEMMAGRSP 450
FDIITDNPDM NTEDYLFQVI LEKPIRIPRF LSVKASHVLK GFLNKDPKER 500
LGCRPQTGFS DIKSHAFFRS IDWDLLEKKQ ALPPFQPQIT DDYGLDNFDT 550
QFTSEPVQLT PDDEDAIKRI DQSEFEGFEY INPLLLSTEE SV 600

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