POLB is a known signal protein, which is involved in the following pathway(s)
Scaffold Protein(s) | Related Pathway(s) | PMID |
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XRCC1 | POLB->LIG3 | Reconstitution of DNA base excision-repair with purified human proteins |
Reference: interaction between DNA polymerase beta and the XRCC1 protein.
PMID:Reconstitution of DNA base excision-repair with purified human proteins
The sequence of POLB
Amino acids in red are phosphorylation sites determined by MS/MS
MSKRKAPQET LNGGITDMLT ELANFEKNVS QAIHKYNAYR KAASVIAKYP 50 HKIKSGAEAK KLPGVGTKIA EKIDEFLATG KLRKLEKIRQ DDTSSSINFL 100 TRVSGIGPSA ARKFVDEGIK TLEDLRKNED KLNHHQRIGL KYFGDFEKRI 150 PREEMLQMQD IVLNEVKKVD SEYIATVCGS FRRGAESSGD MDVLLTHPSF 200 TSESTKQPKL LHQVVEQLQK VHFITDTLSK GETKFMGVCQ LPSKNDEKEY 250 PHRRIDIRLI PKDQYYCGVL YFTGSDIFNK NMRAHALEKG FTINEYTIRP 300 LGVTGVAGEP LPVDSEKDIF DYIQWKYREP KDRSE
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