PDGFRB is a predicted scaffold protein, which is related to the following pathway(s).

PDGFRA->SRC->ARAF
PDGFRA->SRC->CBL
PDGFRA->SRC->GRB10
PDGFRA->SRC->ITGB3
PDGFRA->SRC->PIK3R1
PDGFRA->SRC->PTK2
PDGFRA->SRC->RAF1
PDGFRA->SRC->SHC1
PDGFRA->SRC->STAT1
PDGFRA->SRC->STAT3
PDGFRA->SRC->STAT5A
PDGFRA->SRC->STAT5B
PDGFRA->SRC->EGFR->CBL
PDGFRA->SRC->EGFR->CRK
PDGFRA->SRC->EGFR->GAB1
PDGFRA->SRC->EGFR->GRB2
PDGFRA->SRC->EGFR->PLCG1
PDGFRA->SRC->EGFR->PTPN1
PDGFRA->SRC->EGFR->RASA1
PDGFRA->SRC->EGFR->STAT1
PDGFRA->SRC->EGFR->STAT5B
PDGFRA->SRC->EGFR->VAV2


PDGFRB is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
SHC1PDGFRB->FYN->CBL
SHC1PDGFRB->FYN->CD247
SHC1PDGFRB->FYN->FCGR2A
SHC1PDGFRB->FYN->PLCG2
PTPN11PDGFRB->FYN->CAV1
PTPN11PDGFRB->FYN->CBL
PTPN11PDGFRB->FYN->PLCG2
PTPN11PDGFRB->FYN->SHC1
PTPN11PDGFRB->FYN->SLAMF1
PLCG1PDGFRB->FYN->CBL
PLCG1PDGFRB->FYN->SHC1
CBLPDGFRB->FYN->FYB
CBLPDGFRB->FYN->ITCH
CBLPDGFRB->FYN->SHC1
PTK2PDGFRB->FYN->CD79B
PTK2PDGFRB->FYN->SHC1
PTK2PDGFRB->FYN->TGFB1I1
PIK3R2PDGFRB->FYN->CBL
PIK3R2PDGFRB->FYN->SHC1
SRCSYK->PRKCA->ADRBK1->PDGFRB->PTPN11
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->CAV1
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->CBL
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->CTNNB1
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->FYB
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->GRB10
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->MAP2
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->NMT1
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->SHC1
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->SKAP1
CRKPDGFRB->FYN->CBL
CRKPDGFRB->FYN->SHC1


The sequence of PDGFRB

Amino acids in red are phosphorylation sites determined by MS/MS

MRLPGAMPAL ALKGELLLLS LLLLLEPQIS QGLVVTPPGP ELVLNVSSTF 50
VLTCSGSAPV VWERMSQEPP QEMAKAQDGT FSSVLTLTNL TGLDTGEYFC 100
THNDSRGLET DERKRLYIFV PDPTVGFLPN DAEELFIFLT EITEITIPCR 150
VTDPQLVVTL HEKKGDVALP VPYDHQRGFF GIFEDRSYIC KTTIGDREVD 200
SDAYYVYRLQ VSSINVSVNA VQTVVRQGEN ITLMCIVIGN EVVNFEWTYP 250
RKESGRLVEP VTDFLLDMPY HIRSILHIPS AELEDSGTYT CNVTESVNDH 300
QDEKAINITV VESGYVRLLG EVGTLQFAEL HRSRTLQVVF EAYPPPTVLW 350
FKDNRTLGDS SAGEIALSTR NVSETRYVSE LTLVRVKVAE AGHYTMRAFH 400
EDAEVQLSFQ LQINVPVRVL ELSESHPDSG EQTVRCRGRG MPQPNIIWSA 450
CRDLKRCPRE LPPTLLGNSS EEESQLETNV TYWEEEQEFE VVSTLRLQHV 500
DRPLSVRCTL RNAVGQDTQE VIVVPHSLPF KVVVISAILA LVVLTIISLI 550
ILIMLWQKKP RYEIRWKVIE SVSSDGHEYI YVDPMQLPYD STWELPRDQL 600
VLGRTLGSGA FGQVVEATAH GLSHSQATMK VAVKMLKSTA RSSEKQALMS 650
ELKIMSHLGP HLNVVNLLGA CTKGGPIYII TEYCRYGDLV DYLHRNKHTF 700
LQHHSDKRRP PSAELYSNAL PVGLPLPSHV SLTGESDGGY MDMSKDESVD 750
YVPMLDMKGD VKYADIESSN YMAPYDNYVP SAPERTCRAT LINESPVLSY 800
MDLVGFSYQV ANGMEFLASK NCVHRDLAAR NVLICEGKLV KICDFGLARD 850
IMRDSNYISK GSTFLPLKWM APESIFNSLY TTLSDVWSFG ILLWEIFTLG 900
GTPYPELPMN EQFYNAIKRG YRMAQPAHAS DEIYEIMQKC WEEKFEIRPP 950
FSQLVLLLER LLGEGYKKKY QQVDEEFLRS DHPAILRSQA RLPGFHGLRS 1000
PLDTSSVLYT AVQPNEGDND YIIPLPDPKP EVADEGPLEG SPSLASSTLN 1050
EVNTSSTISC DSPLEPQDEP EPEPQLELQV EPEPELEQLP DSGCPAPRAE 1100
AEDSFL

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