PDGFRA is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
PTPN11PDGFRA->SRC->BCAR1
PTPN11PDGFRA->SRC->BDKRB2
PTPN11PDGFRA->SRC->CAV1
PTPN11PDGFRA->SRC->CBL
PTPN11PDGFRA->SRC->CD33
PTPN11PDGFRA->SRC->IGF1R
PTPN11PDGFRA->SRC->KIT
PTPN11PDGFRA->SRC->MPZL1
PTPN11PDGFRA->SRC->PIK3R1
PTPN11PDGFRA->SRC->PLCG2
PTPN11PDGFRA->SRC->PTPN6
PTPN11PDGFRA->SRC->PXN
PTPN11PDGFRA->SRC->SHC1
PTPN11PDGFRA->SRC->SPRY2
PTPN11PDGFRA->SRC->STAT1
PTPN11PDGFRA->SRC->STAT3
PTPN11PDGFRA->SRC->STAT5A
PTPN11PDGFRA->SRC->STAT5B
PTPN11PDGFRA->SRC->EGFR->CBL
PTPN11PDGFRA->SRC->EGFR->GAB1
PTPN11PDGFRA->SRC->EGFR->GRB2
PTPN11PDGFRA->SRC->EGFR->PLCG1
PTPN11PDGFRA->SRC->EGFR->STAT1
PTPN11PDGFRA->SRC->EGFR->STAT5B
PTPN11PDGFRA->SRC->PTK2->PXN
PLCG1PDGFRA->SRC->CBL
PLCG1PDGFRA->SRC->GNB2L1
PLCG1PDGFRA->SRC->KIT
PLCG1PDGFRA->SRC->PTK2
PLCG1PDGFRA->SRC->SHC1
PLCG1PDGFRA->SRC->ABL1->BCR
PLCG1PDGFRA->SRC->ABL1->CBL
PLCG1PDGFRA->SRC->ABL1->PRKD1
PLCG1PDGFRA->SRC->EGFR->CBL
PLCG1PDGFRA->SRC->EGFR->GAB1
PLCG1PDGFRA->SRC->EGFR->GRB2
PLCG1PDGFRA->SRC->EGFR->RASA1
PLCG1PDGFRA->SRC->ABL1->BTK->TEC
PLCG1PDGFRA->SRC->ABL1->BTK->WAS
PLCG1PDGFRA->SRC->ABL1->BTK->ITK->CD28
PLCG1PDGFRA->SRC->ABL1->BTK->ITK->TEC
CBLPDGFRA->SRC->INPPL1
CBLPDGFRA->SRC->KIT
CBLPDGFRA->SRC->PIK3R1
CBLPDGFRA->SRC->PTPN6
CBLPDGFRA->SRC->PXN
CBLPDGFRA->SRC->SHC1
CBLPDGFRA->SRC->SPRY2
CBLPDGFRA->SRC->STAT5A
CBLPDGFRA->SRC->STAT5B
CBLPDGFRA->SRC->ABL1->BCR
CBLPDGFRA->SRC->ABL1->CRK
CBLPDGFRA->SRC->ABL1->CRKL
CBLPDGFRA->SRC->EGFR->CRK
CBLPDGFRA->SRC->EGFR->GRB2
CBLPDGFRA->SRC->EGFR->PLCG1
CBLPDGFRA->SRC->EGFR->STAT5B
CBLPDGFRA->SRC->EGFR->VAV2
CBLPDGFRA->SRC->ABL1->BTK->ITK
GRB2PDGFRA->SRC->ABL1->BCR
GRB2PDGFRA->SRC->ABL1->CBL
GRB2PDGFRA->SRC->ABL1->CRK
GRB2PDGFRA->SRC->ABL1->CRKL
GRB2PDGFRA->SRC->ABL1->MUC1
GRB2PDGFRA->SRC->ABL1->WASF2
GRB2PDGFRA->SRC->EGFR->CBL
GRB2PDGFRA->SRC->EGFR->CRK
GRB2PDGFRA->SRC->EGFR->GAB1
GRB2PDGFRA->SRC->EGFR->MUC1
GRB2PDGFRA->SRC->EGFR->PLCG1
GRB2PDGFRA->SRC->EGFR->PTPN1
GRB2PDGFRA->SRC->EGFR->RASA1
GRB2PDGFRA->SRC->EGFR->VAV2
GRB2PDGFRA->SRC->PTK2->PXN
STAT5BPDGFRA->SRC->CBL
STAT5BPDGFRA->SRC->KIT
STAT5BPDGFRA->SRC->PTPN6
STAT5BPDGFRA->SRC->SHC1
STAT5BPDGFRA->SRC->STAT1
STAT5BPDGFRA->SRC->STAT3
STAT5BPDGFRA->SRC->STAT5A
STAT5BPDGFRA->SRC->EGFR->CBL
STAT5BPDGFRA->SRC->EGFR->CRK
STAT5BPDGFRA->SRC->EGFR->PTPN1
STAT5BPDGFRA->SRC->EGFR->STAT1
CAV1PDGFRA->SRC->BMX
CAV1PDGFRA->SRC->CAV2
CAV1PDGFRA->SRC->CTNNB1
CAV1PDGFRA->SRC->DAG1
CAV1PDGFRA->SRC->ESR1
CAV1PDGFRA->SRC->LRP1
CAV1PDGFRA->SRC->PTPN6
CAV1PDGFRA->SRC->EGFR->PTPN1
CAV1PDGFRA->SRC->ABL1->BTK->BMX
SHBPDGFRA->SRC->PIK3R1
STAT5APDGFRA->SRC->BMX
STAT5APDGFRA->SRC->CBL
STAT5APDGFRA->SRC->ESR1
STAT5APDGFRA->SRC->KIT
STAT5APDGFRA->SRC->SHC1
STAT5APDGFRA->SRC->STAT1
STAT5APDGFRA->SRC->STAT3
STAT5APDGFRA->SRC->STAT5B
STAT5APDGFRA->SRC->EGFR->CBL
STAT5APDGFRA->SRC->EGFR->CRK
STAT5APDGFRA->SRC->EGFR->PTPN1
STAT5APDGFRA->SRC->EGFR->STAT1
STAT5APDGFRA->SRC->EGFR->STAT5B
PDGFRBPDGFRA->SRC->ARAF
PDGFRBPDGFRA->SRC->CBL
PDGFRBPDGFRA->SRC->GRB10
PDGFRBPDGFRA->SRC->ITGB3
PDGFRBPDGFRA->SRC->PIK3R1
PDGFRBPDGFRA->SRC->PTK2
PDGFRBPDGFRA->SRC->RAF1
PDGFRBPDGFRA->SRC->SHC1
PDGFRBPDGFRA->SRC->STAT1
PDGFRBPDGFRA->SRC->STAT3
PDGFRBPDGFRA->SRC->STAT5A
PDGFRBPDGFRA->SRC->STAT5B
PDGFRBPDGFRA->SRC->EGFR->CBL
PDGFRBPDGFRA->SRC->EGFR->CRK
PDGFRBPDGFRA->SRC->EGFR->GAB1
PDGFRBPDGFRA->SRC->EGFR->GRB2
PDGFRBPDGFRA->SRC->EGFR->PLCG1
PDGFRBPDGFRA->SRC->EGFR->PTPN1
PDGFRBPDGFRA->SRC->EGFR->RASA1
PDGFRBPDGFRA->SRC->EGFR->STAT1
PDGFRBPDGFRA->SRC->EGFR->STAT5B
PDGFRBPDGFRA->SRC->EGFR->VAV2
CRKPDGFRA->SRC->BCAR1
CRKPDGFRA->SRC->CBL
CRKPDGFRA->SRC->IGF1R
CRKPDGFRA->SRC->KIT
CRKPDGFRA->SRC->PIK3R1
CRKPDGFRA->SRC->PLSCR1
CRKPDGFRA->SRC->PXN
CRKPDGFRA->SRC->RAPGEF1
CRKPDGFRA->SRC->SHC1
CRKPDGFRA->SRC->STAT5A
CRKPDGFRA->SRC->STAT5B
CRKPDGFRA->SRC->ABL1->CBL
CRKPDGFRA->SRC->ABL1->CRKL
CRKPDGFRA->SRC->ABL1->PLSCR1
CRKPDGFRA->SRC->EGFR->CBL
CRKPDGFRA->SRC->EGFR->GAB1
CRKPDGFRA->SRC->EGFR->GRB2
CRKPDGFRA->SRC->EGFR->STAT5B
CRKPDGFRA->SRC->PTK2->PXN
PIK3R1PDGFRA->SRC->ABL1->CBL
PIK3R1PDGFRA->SRC->ABL1->CRK
PIK3R1PDGFRA->SRC->ABL1->CRKL
PIK3R1PDGFRA->SRC->ABL1->NFKBIA
PIK3R1PDGFRA->SRC->EGFR->CBL
PIK3R1PDGFRA->SRC->EGFR->CRK
PIK3R1PDGFRA->SRC->EGFR->GAB1
PIK3R1PDGFRA->SRC->EGFR->GRB2
PIK3R1PDGFRA->SRC->EGFR->HGS
PIK3R1PDGFRA->SRC->EGFR->RASA1
PIK3R1PDGFRA->SRC->IGF1R->CRK
PIK3R1PDGFRA->SRC->PTK2->PXN
ITGB3PDGFRA->SRC->PDPK1
ITGB3PDGFRA->SRC->PTK2
ITGB3PDGFRA->SRC->SHC1


The sequence of PDGFRA

Amino acids in red are phosphorylation sites determined by MS/MS

MGTSHPAFLV LGCLLTGLSL ILCQLSLPSI LPNENEKVVQ LNSSFSLRCF 50
GESEVSWQYP MSEEESSDVE IRNEENNSGL FVTVLEVSSA SAAHTGLYTC 100
YYNHTQTEEN ELEGRHIYIY VPDPDVAFVP LGMTDYLVIV EDDDSAIIPC 150
RTTDPETPVT LHNSEGVVPA SYDSRQGFNG TFTVGPYICE ATVKGKKFQT 200
IPFNVYALKA TSELDLEMEA LKTVYKSGET IVVTCAVFNN EVVDLQWTYP 250
GEVKGKGITM LEEIKVPSIK LVYTLTVPEA TVKDSGDYEC AARQATREVK 300
EMKKVTISVH EKGFIEIKPT FSQLEAVNLH EVKHFVVEVR AYPPPRISWL 350
KNNLTLIENL TEITTDVEKI QEIRYRSKLK LIRAKEEDSG HYTIVAQNED 400
AVKSYTFELL TQVPSSILDL VDDHHGSTGG QTVRCTAEGT PLPDIEWMIC 450
KDIKKCNNET SWTILANNVS NIITEIHSRD RSTVEGRVTF AKVEETIAVR 500
CLAKNLLGAE NRELKLVAPT LRSELTVAAA VLVLLVIVII SLIVLVVIWK 550
QKPRYEIRWR VIESISPDGH EYIYVDPMQL PYDSRWEFPR DGLVLGRVLG 600
SGAFGKVVEG TAYGLSRSQP VMKVAVKMLK PTARSSEKQA LMSELKIMTH 650
LGPHLNIVNL LGACTKSGPI YIITEYCFYG DLVNYLHKNR DSFLSHHPEK 700
PKKELDIFGL NPADESTRSY VILSFENNGD YMDMKQADTT QYVPMLERKE 750
VSKYSDIQRS LYDRPASYKK KSMLDSEVKN LLSDDNSEGL TLLDLLSFTY 800
QVARGMEFLA SKNCVHRDLA ARNVLLAQGK IVKICDFGLA RDIMHDSNYV 850
SKGSTFLPVK WMAPESIFDN LYTTLSDVWS YGILLWEIFS LGGTPYPGMM 900
VDSTFYNKIK SGYRMAKPDH ATSEVYEIMV KCWNSEPEKR PSFYHLSEIV 950
ENLLPGQYKK SYEKIHLDFL KSDHPAVARM RVDSDNAYIG VTYKNEEDKL 1000
KDWEGGLDEQ RLSADSGYII PLPDIDPVPE EEDLGKRNRH SSQTSEESAI 1050
ETGSSSSTFI KREDETIEDI DMMDDIGIDS SDLVEDSFL

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