MAPK14 is a predicted scaffold protein, which is related to the following pathway(s).

MAP2K1->MAPK1->DUSP1
MAP2K1->MAPK1->DUSP16
MAP2K1->MAPK1->DUSP6
MAP2K1->MAPK1->MAPKAPK5
MAP2K1->MAPK1->MBP
MAP2K1->MAPK1->NFATC4
MAP2K1->MAPK1->PLA2G4A
MAP2K1->MAPK1->SMAD3
MAP2K4->MAPK8->ATF2
MAP2K4->MAPK8->BCL2
MAP2K1->MAPK1->EGFR->GRB2
MAP2K1->MAPK1->EGFR->STAT1
MAP2K1->MAPK1->MAPKAPK2->CDC25B
MAP2K1->MAPK1->MAPKAPK2->CREB1
MAP2K1->MAPK1->MAPKAPK2->EEF2K
MAP2K1->MAPK1->MAPKAPK2->ESR1
MAPK1->MAP2K1->MAPK3->DUSP1
MAPK1->MAP2K1->MAPK3->DUSP6
MAPK1->MAP2K1->MAPK3->ELK1
MAPK1->MAP2K1->MAPK3->ESR1
MAPK1->MAP2K1->MAPK3->MBP
MAPK1->MAP2K1->MAPK3->MKNK1
MAPK1->MAP2K1->MAPK3->NFATC4
MAPK1->MAP2K1->MAPK3->EGFR->GRB2
MAPK1->MAP2K1->MAPK3->EGFR->STAT1


MAPK14 is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
RPS6KA4MAPK14->CREB1
DYRK1BMAP2K3->MAPK14



MAPK14 is a known signal protein, which is involved in the following pathway(s)

Scaffold Protein(s)Related Pathway(s)PMID
DLG1MAPK14->NFAT17187070

Reference:Scaffold protein Dlgh1 coordinates alternative p38 kinase activation, directing T cell receptor signals toward NFAT but not NF-kappaB transcription factors.

PMID:17187070


The sequence of MAPK14

Amino acids in red are phosphorylation sites determined by MS/MS

MTSKGPEEEH PSVTLFRQYL RIRTVQPKPD YGAAVAFFEE TARQLGLGCQ 50
KVEVAPGYVV TVLTWPGTNP TLSSILLNSH TDVVPVFKEH WSHDPFEAFK 100
DSEGYIYARG AQDMKCVSIQ YLEAVRRLKV EGHRFPRTIH MTFVPDEEVG 150
GHQGMELFVQ RPEFHALRAG FALDEGIANP TDAFTVFYSE RSPWWVRVTS 200
TGRPGHASRF MEDTAAEKLH KVVNSILAFR EKEWQRLQSN PHLKEGSVTS 250
VNLTKLEGGV AYNVIPATMS ASFDFRVAPD VDFKAFEEQL QSWCQAAGEG 300
VTLEFAQKWM HPQVTPTDDS NPWWAAFSRV CKDMNLTLEP EIMPAATDNR 350
YIRAVGVPAL GFSPMNRTPV LLHDHDERLH EAVFLRGVDI YTRLLPALAS 400
VPALPSDS

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