MAP2K7 is a predicted scaffold protein, which is related to the following pathway(s).

MAP3K11->MAP2K4->MAPK8->MAPK8IP1
MAP3K11->MAP2K4->MAPK9->MAPK8IP1
MAP3K5->MAP2K4->MAPK8->MAPK8IP1
MAP3K5->MAP2K4->MAPK9->MAPK8IP1


MAP2K7 is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
DUSP19MAP2K7->MAPK9
DUSP22MAP2K7->MAPK8
MAP3K2MAP2K7->MAPK8->SFN
MAP3K2MAP2K7->MAPK8->YWHAB
MAP3K2MAP2K7->MAPK8->YWHAZ
MAPK8IP3MAP3K1->MAP2K7->MAPK10
MAPK8IP3MAP3K1->MAP2K7->MAPK8->MAPK8IP1
MAPK8IP3MAP3K1->MAP2K7->MAPK9->MAPK8IP1
MAP2K4MAP3K1->MAP2K7->MAPK10
MAP2K4MAP3K1->MAP2K7->MAPK8
MAP2K4MAP3K1->MAP2K7->MAPK9
MAPK8IP2MAP2K7->MAPK8->MAPK8IP1
MAPK8IP2MAP2K7->MAPK9->MAPK8IP1



MAP2K7 is a known signal protein, which is involved in the following pathway(s)

Scaffold Protein(s)Related Pathway(s)PMID
SH3RF1ARHGEF2->MAP3K11->MAP2K4->MAP2K7->MAPK812514131

Reference:POSH acts as a scaffold for a multiprotein complex that mediates JNK activation in apoptosis.

PMID:12514131


The sequence of MAP2K7

Amino acids in red are phosphorylation sites determined by MS/MS

MAASSLEQKL SRLEAKLKQE NREARRRIDL NLDISPQRPR PTLQLPLAND 50
GGSRSPSSES SPQHPTPPAR PRHMLGLPST LFTPRSMESI EIDQKLQEIM 100
KQTGYLTIGG QRYQAEINDL ENLGEMGSGT CGQVWKMRFR KTGHVIAVKQ 150
MRRSGNKEEN KRILMDLDVV LKSHDCPYIV QCFGTFITNT DVFIAMELMG 200
TCAEKLKKRM QGPIPERILG KMTVAIVKAL YYLKEKHGVI HRDVKPSNIL 250
LDERGQIKLC DFGISGRLVD SKAKTRSAGC AAYMAPERID PPDPTKPDYD 300
IRADVWSLGI SLPCPSPSQV ELATGQFPYK NCKTDFEVLT KVLQEEPPLL 350
PGHMGFSGDF QSFVKDCLTK DHRKRPKYNK LLEHSFIKRY ETLEVDVASW 400
FKDVMAKTES PRTSGVLSQP HLPFFR

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