| LCK | -> | ZAP70 | -> | GAB2 | LCK | -> | ZAP70 | -> | LCP2 | SYK | -> | MAP4K1 | -> | LCP2 |
LAT is a known signal protein, which is involved in the following pathway(s)
LAT is a known signal protein, which is involved in the following pathway(s)
| Scaffold Protein(s) | Related Pathway(s) | PMID |
|---|---|---|
| LCP2 | GRAP2->LAT | 10224278 |
Reference:Grf40, A novel Grb2 family member, is involved in T cell signaling through interaction with SLP-76 and LAT.
PMID:10224278
The sequence of LAT
Amino acids in red are phosphorylation sites determined by MS/MS
MEEAILVPCV LGLLLLPILA MLMALCVHCH RLPGSYDSTS SDSLYPRGIQ 50
FKRPHTVAPW PPAYPPVTSY PPLSQPDLLP IPRSPQPLGG SHRTPSSRRD 100
SDGANSVASY ENEGASGIRG AQAGWGVWGP SWTRLTPVSL PPEPACEDAD 150
EDEDDYHNPG YLVVLPDSTP ATSTAAPSAP ALSTPGIRDS AFSMESIDDY 200
VNVPESGESA EASLDGSREY VNVSQELHPG AAKTEPAALS SQEAEEVEEE 250
GAPDYENLQE LN