KSR2 is a predicted scaffold protein, which is related to the following pathway(s).

MAP3K8->MAP2K1->MAPK1
MAP3K8->MAP2K1->MAPK3
MAPK1->MAP2K1->MAPK3
RAF1->MAP2K1->MAPK1
RAF1->MAP2K1->MAPK3



KSR2 is a known scaffold protein, which is related to the following pathway(s).

MEK1->ERK

Reference:Scaffold proteins and immune-cell signalling.

PMID:19104498


The sequence of KSR2

Amino acids in red are phosphorylation sites determined by MS/MS

MTDEQVCETV EKYGANREEC ARLNASLSCL RNVHMSGGNL SKQDWTIQWP 50
TTETGKENNP VCPPEPTPWI RTHLSQSPRV PSKCVQHYCH TSPTPGAPVY 100
THVDRLTVDA YPGLCPPPPL ESGHRSLPPS PRQRHAVRTP PRTPNIVTTV 150
TPPGTPPMRK KNKLKPPGTP PPSSRKLIHL IPGFTALHRS KSHEFQLGHR 200
VDEAHTPKAK KKSKPLNLKI HSSVGSCENI PSQQRSPLLS ERSLRSFFVG 250
HAPFLPSTPP VHTEANFSAN TLSVPRWSPQ IPRRDLGNSI KHRFSTKYWM 300
SQTCTVCGKG MLFGLKCKNC KLKCHNKCTK EAPPCHLLII HRGDPARLVR 350
TESVPCDINN PLRKPPRYSD LHISQTLPKT NKINKDHIPV PYQPDSSSNP 400
SSTTSSTPSS PAPPLPPSAT PPSPLHPSPQ CTRQQKNFNL PASHYYKYKQ 450
QFIFPDVVPV PETPTRAPQV ILHPVTSNPI LEGNPLLQIE VEPTSENEEV 500
HDEAEESEDD FEEMNLSLLS ARSFPRKASQ TSIFLQEWDI PFEQLEIGEL 550
IGKGRFGQVY HGRWHGEVAI RLIDIERDNE DQLKAFKREV MAYRQTRHEN 600
VVLFMGACMS PPHLAIITSL CKGRTLYSVV RDAKIVLDVN KTRQIAQEIV 650
KGMGYLHAKG ILHKDLKSKN VFYDNGKVVI TDFGLFSISG VLQAGRREDK 700
LRIQNGWLCH LAPEIIRQLS PDTEEDKLPF SKHSDVFALG TIWYELHARE 750
WPFKTQPAEA IIWQMGTGMK PNLSQIGMGK EISDILLFCW AFEQEERPTF 800
TKLMDMLEKL PKRNRRLSHP GHFWKSAEL

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