ITGB3 is a predicted scaffold protein, which is related to the following pathway(s).

PDGFRA->SRC->PDPK1
PDGFRA->SRC->PTK2
PDGFRA->SRC->SHC1


ITGB3 is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
PECAM1CSK->SRC->ITGB3
DAB2CSK->SRC->ITGB3
SHC1CSK->SRC->ITGB3
DAB1CDK5->SRC->ITGB3
DOK1CSK->SRC->ITGB3
PTK2CSK->SRC->ITGB3
PDGFRBPDGFRA->SRC->ITGB3


The sequence of ITGB3

Amino acids in red are phosphorylation sites determined by MS/MS

MRARPRPRPL WATVLALGAL AGVGVGGPNI CTTRGVSSCQ QCLAVSPMCA 50
WCSDEALPLG SPRCDLKENL LKDNCAPESI EFPVSEARVL EDRPLSDKGS 100
GDSSQVTQVS PQRIALRLRP DDSKNFSIQV RQVEDYPVDI YYLMDLSYSM 150
KDDLWSIQNL GTKLATQMRK LTSNLRIGFG AFVDKPVSPY MYISPPEALE 200
NPCYDMKTTC LPMFGYKHVL TLTDQVTRFN EEVKKQSVSR NRDAPEGGFD 250
AIMQATVCDE KIGWRNDASH LLVFTTDAKT HIALDGRLAG IVQPNDGQCH 300
VGSDNHYSAS TTMDYPSLGL MTEKLSQKNI NLIFAVTENV VNLYQNYSEL 350
IPGTTVGVLS MDSSNVLQLI VDAYGKIRSK VELEVRDLPE ELSLSFNATC 400
LNNEVIPGLK SCMGLKIGDT VSFSIEAKVR GCPQEKEKSF TIKPVGFKDS 450
LIVQVTFDCD CACQAQAEPN SHRCNNGNGT FECGVCRCGP GWLGSQCECS 500
EEDYRPSQQD ECSPREGQPV CSQRGECLCG QCVCHSSDFG KITGKYCECD 550
DFSCVRYKGE MCSGHGQCSC GDCLCDSDWT GYYCNCTTRT DTCMSSNGLL 600
CSGRGKCECG SCVCIQPGSY GDTCEKCPTC PDACTFKKEC VECKKFDRGA 650
LHDENTCNRY CRDEIESVKE LKDTGKDAVN CTYKNEDDCV VRFQYYEDSS 700
GKSILYVVEE PECPKGPDIL VVLLSVMGAI LLIGLAALLI WKLLITIHDR 750
KEFAKFEEER ARAKWDTANN PLYKEATSTF TNITYRGT

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