IL2RB is a predicted scaffold protein, which is related to the following pathway(s).

JAK3->JAK1->STAT1
JAK3->JAK1->STAT3


IL2RB is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
SHC1MAPK1->LCK->IL2RB
STAT5AMAPK1->LCK->IL2RB
STAT5AMAPK3->LCK->IL2RB
RAF1MAP2K2->MAPK3->LCK->IL2RB
RAF1MAPK1->MAP2K1->MAPK3->LCK->IL2RB
RAF1PAK1->MAP2K1->MAPK1->LCK->IL2RB
RAF1MAPK1->PAK1->MAP2K1->MAPK3->LCK->IL2RB


The sequence of IL2RB

Amino acids in red are phosphorylation sites determined by MS/MS

MAAPALSWRL PLLILLLPLA TSWASAAVNG TSQFTCFYNS RANISCVWSQ 50
DGALQDTSCQ VHAWPDRRRW NQTCELLPVS QASWACNLIL GAPDSQKLTT 100
VDIVTLRVLC REGVRWRVMA IQDFKPFENL RLMAPISLQV VHVETHRCNI 150
SWEISQASHY FERHLEFEAR TLSPGHTWEE APLLTLKQKQ EWICLETLTP 200
DTQYEFQVRV KPLQGEFTTW SPWSQPLAFR TKPAALGKDT IPWLGHLLVG 250
LSGAFGFIIL VYLLINCRNT GPWLKKVLKC NTPDPSKFFS QLSSEHGGDV 300
QKWLSSPFPS SSFSPGGLAP EISPLEVLER DKVTQLLLQQ DKVPEPASLS 350
SNHSLTSCFT NQGYFFFHLP DALEIEACQV YFTYDPYSEE DPDEGVAGAP 400
TGSSPQPLQP LSGEDDAYCT FPSRDDLLLF SPSLLGGPSP PSTAPGGSGA 450
GEERMPPSLQ ERVPRDWDPQ PLGPPTPGVP DLVDFQPPPE LVLREAGEEV 500
PDAGPREGVS FPWSRPPGQG EFRALNARLP LNTDAYLSLQ ELQGQDPTHL 550
V

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