GNAI1 is a known signal protein, which is involved in the following pathway(s)
GNAI1 is a known signal protein, which is involved in the following pathway(s)
| Scaffold Protein(s) | Related Pathway(s) | PMID |
|---|---|---|
| CAV1 | GNAI1->HRAS->SRC | 8910575 |
Reference:Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases.
PMID:8910575
The sequence of GNAI1
Amino acids in red are phosphorylation sites determined by MS/MS
MGCTLSAEDK AAVERSKMID RNLREDGEKA AREVKLLLLG AGESGKSTIV 50
KQMKIIHEAG YSEEECKQYK AVVYSNTIQS IIAIIRAMGR LKIDFGDSAR 100
ADDARQLFVL AGAAEEGFMT AELAGVIKRL WKDSGVQACF NRSREYQLND 150
SAAYYLNDLD RIAQPNYIPT QQDVLRTRVK TTGIVETHFT FKDLHFKMFD 200
VGGQRSERKK WIHCFEGVTA IIFCVALSDY DLVLAEDEEM NRMHESMKLF 250
DSICNNKWFT DTSIILFLNK KDLFEEKIKK SPLTICYPEY AGSNTYEEAA 300
AYIQCQFEDL NKRKDTKEIY THFTCATDTK NVQFVFDAVT DVIIKNNLKD 350
CGLF