ESR1 is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
PTPN1SRC->ESR1
PTPN1MAPK1->GSK3B->ESR1
SHC1CSK->SRC->ESR1
SHC1MAPK1->LCK->ESR1
SHC1MAPK1->MAPKAPK2->ESR1
SHC1SYK->PTK2B->ESR1
BRCA1CSNK2A1->CDC2->CDK7->ESR1
EGFRMAP2K1->MAPK1->PAK1->ESR1
IGF1RCSK->SRC->ESR1
CAV1CSK->SRC->ESR1
CAV1PDGFRA->SRC->ESR1
STAT5AMAPK1->LCK->ESR1
STAT5AMAPK3->LCK->ESR1
STAT5APDGFRA->SRC->ESR1
PTPN6SYK->PTK2B->ESR1
CCNHCDK2->CDK7->ESR1
MAPK14MAP2K1->MAPK1->MAPKAPK2->ESR1
MAPK14MAPK1->MAP2K1->MAPK3->ESR1
SNURFSRC->ESR1


The sequence of ESR1

Amino acids in red are phosphorylation sites determined by MS/MS

MTMTLHTKAS GMALLHQIQG NELEPLNRPQ LKIPLERPLG EVYLDSSKPA 50
VYNYPEGAAY EFNAAAAANA QVYGQTGLPY GPGSEAAAFG SNGLGGFPPL 100
NSVSPSPLML LHPPPQLSPF LQPHGQQVPY YLENEPSGYT VREAGPPAFY 150
RPNSDNRRQG GRERLASTND KGSMAMESAK ETRYCAVCND YASGYHYGVW 200
SCEGCKAFFK RSIQGHNDYM CPATNQCTID KNRRKSCQAC RLRKCYEVGM 250
MKGGIRKDRR GGRMLKHKRQ RDDGEGRGEV GSAGDMRAAN LWPSPLMIKR 300
SKKNSLALSL TADQMVSALL DAEPPILYSE YDPTRPFSEA SMMGLLTNLA 350
DRELVHMINW AKRVPGFVDL TLHDQVHLLE CAWLEILMIG LVWRSMEHPG 400
KLLFAPNLLL DRNQGKCVEG MVEIFDMLLA TSSRFRMMNL QGEEFVCLKS 450
IILLNSGVYT FLSSTLKSLE EKDHIHRVLD KITDTLIHLM AKAGLTLQQQ 500
HQRLAQLLLI LSHIRHMSNK GMEHLYSMKC KNVVPLYDLL LEMLDAHRLH 550
APTSRGGASV EETDQSHLAT AGSTSSHSLQ KYYITGEAEG FPATV 600

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