CRKL is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
SHC1CSK->SRC->ABL1->CRKL
CBLCSK->SRC->ABL1->CRKL
CBLPDGFRA->SRC->ABL1->CRKL
DOK1CSK->SRC->ABL1->CRKL
GRB2PDGFRA->SRC->ABL1->CRKL
PXNCSK->SRC->ABL1->CRKL
CRKPDGFRA->SRC->ABL1->CRKL
KITSRC->ABL1->CRKL
PIK3R1PDGFRA->SRC->ABL1->CRKL
BCAR1SRC->ABL1->CRKL
MAP4K5ABL1->CRKL
EVLSRC->ABL1->CRKL


The sequence of CRKL

Amino acids in red are phosphorylation sites determined by MS/MS

MSSARFDSSD RSAWYMGPVS RQEAQTRLQG QRHGMFLVRD SSTCPGDYVL 50
SVSENSRVSH YIINSLPNRR FKIGDQEFDH LPALLEFYKI HYLDTTTLIE 100
PAPRYPSPPM GSVSAPNLPT AEDNLEYVRT LYDFPGNDAE DLPFKKGEIL 150
VIIEKPEEQW WSARNKDGRV GMIPVPYVEK LVRSSPHGKH GNRNSNSYGI 200
PEPAHAYAQP QTTTPLPAVS GSPGAAITPL PSTQNGPVFA KAIQKRVPCA 250
YDKTALALEV GDIVKVTRMN INGQWEGEVN GRKGLFPFTH VKIFDPQNPD 300
ENE

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