CDK2 is a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
BRCA1CDK2->CDK7->CDC2->APLP2
BRCA1CDK2->CDK7->CDC2->CSNK2B
BRCA1CDK2->CDK7->CDC2->E2F1
BRCA1CDK2->CDK7->CDC2->FANCG
BRCA1CDK2->CDK7->CDC2->PPP1CA
BRCA1CDK2->CDK7->CDK4->RBL1
BRCA1CDK2->CDK7->CDK4->RBL2
BRCA1CDK2->CDK7->CDK4->SMAD3
BRCA1CDK2->CDK7->CDC2->CSNK2A1->AKT1
BRCA1CDK2->CDK7->CDC2->CSNK2A1->HDAC1
BRCA1CDK2->CDK7->CDC2->CSNK2A1->HDAC2
BRCA1CDK2->CDK7->CDC2->CSNK2A1->IFI16
BRCA1CDK2->CDK7->CDC2->CSNK2A1->JUN
BRCA1CDK2->CDK7->CDC2->CSNK2A1->RELA
BRCA1CDK2->CDK7->CDC2->CSNK2A1->XRCC1
SPDY1CDK2->CDKN1B
E2F1CDK2->CDK7->CDC2->HTATIP
CCNE2CDK2->CDKN1A
CCNE2CDK2->CDKN1B
CCNE2CDK2->RBL2
CCNHCDK2->CDK7->ESR1
CCNHCDK2->CDK7->TP53


The sequence of CDK2

Amino acids in red are phosphorylation sites determined by MS/MS

MENFQKVEKI GEGTYGVVYK ARNKLTGEVV ALKKIRLDTE TEGVPSTAIR 50
EISLLKELNH PNIVKLLDVI HTENKLYLVF EFLHQDLKKF MDASALTGIP 100
LPLIKSYLFQ LLQGLAFCHS HRVLHRDLKP QNLLINTEGA IKLADFGLAR 150
AFGVPVRTYT HEVVTLWYRA PEILLGCKYY STAVDIWSLG CIFAEMVTRR 200
ALFPGDSEID QLFRIFRTLG TPDEVVWPGV TSMPDYKPSF PKWARQDFSK 250
VVPPLDEDGR SLLSQMLHYD PNKRISAKAA LAHPFFQDVT KPVPHLRL 300

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