CAV1 is a predicted scaffold protein, which is related to the following pathway(s).

CSK->FYN->CTNNB1
CSK->SRC->BMX
CSK->SRC->CAV2
CSK->SRC->CTNNB1
CSK->SRC->DAG1
CSK->SRC->ESR1
CSK->SRC->LRP1
CSK->SRC->PTPN6
MAPK1->EGFR->PTPN1
MAPK3->EGFR->PTPN1
PDGFRA->SRC->BMX
PDGFRA->SRC->CAV2
PDGFRA->SRC->CTNNB1
PDGFRA->SRC->DAG1
PDGFRA->SRC->ESR1
PDGFRA->SRC->LRP1
PDGFRA->SRC->PTPN6
CSK->SRC->EGFR->PTPN1
PDGFRA->SRC->EGFR->PTPN1
CSK->SRC->ABL1->BTK->BMX
PDGFRA->SRC->ABL1->BTK->BMX



CAV1 is a known scaffold protein, which is related to the following pathway(s).

GNAI1->HRAS->SRC

Reference:Src tyrosine kinases, Galpha subunits, and H-Ras share a common membrane-anchored scaffolding protein, caveolin. Caveolin binding negatively regulates the auto-activation of Src tyrosine kinases.

PMID:8910575


CAV1 is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
PTPN1SRC->CAV1
PLD2CSK->FYN->CAV1
PLD2CSK->SRC->CAV1
GJA1CSK->SRC->CAV1
PTPN11PDGFRA->SRC->CAV1
PTPN11PDGFRB->FYN->CAV1
DNM1CDK5->SRC->CAV1
SRCSYK->PRKCA->ADRBK1->PDGFRB->FYN->CAV1
INSRCSK->SRC->CAV1
DAG1CSK->FYN->CAV1
DAG1CSK->SRC->CAV1



CAV1 is also a known signal protein, which is involved in the following pathway(s)

Scaffold Protein(s)Related Pathway(s)PMID
STRN->CAV1->STRN411707266

Reference:Striatin, a calmodulin-dependent scaffolding protein, directly binds caveolin-1.

PMID:11707266


The sequence of CAV1

Amino acids in red are phosphorylation sites determined by MS/MS

MSGGKYVDSE GHLYTVPIRE QGNIYKPNNK AMADELSEKQ VYDAHTKEID 50
LVNRDPKHLN DDVVKIDFED VIAEPEGTHS FDGIWKASFT TFTVTKYWFY 100
RLLSALFGIP MALIWGIYFA ILSFLHIWAV VPCIKSFLIE IQCISRVYSI 150
YVHTVCDPLF EAVGKIFSNV RINLQKEI

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