CASP9 is a predicted scaffold protein, which is related to the following pathway(s).

MAP2K1->MAPK1->CAPN2
MAP2K2->MAPK3->CAPN2
MAPK1->MAP2K1->MAPK3->CAPN2


CASP9 is also a signaling protein, which is involved in the following pathway(s).

Scaffold Protein(s)Related Pathway(s)
PRKCZMAPK1->MAP2K1->MAPK3->CASP9
PRKCZSRC->RAF1->MAP2K1->MAPK1->CASP9
PRKCZSRC->RAF1->MAP2K1->MAPK3->CASP9


The sequence of CASP9

Amino acids in red are phosphorylation sites determined by MS/MS

MDEADRRLLR RCRLRLVEEL QVDQLWDALL SRELFRPHMI EDIQRAGSGS 50
RRDQARQLII DLETRGSQAL PLFISCLEDT GQDMLASFLR TNRQAAKLSK 100
PTLENLTPVV LRPEIRKPEV LRPETPRPVD IGSGGFGDVG ALESLRGNAD 150
LAYILSMEPC GHCLIINNVN FCRESGLRTR TGSNIDCEKL RRRFSSLHFM 200
VEVKGDLTAK KMVLALLELA QQDHGALDCC VVVILSHGCQ ASHLQFPGAV 250
YGTDGCPVSV EKIVNIFNGT SCPSLGGKPK LFFIQACGGE QKDHGFEVAS 300
TSPEDESPGS NPEPDATPFQ EGLRTFDQLD AISSLPTPSD IFVSYSTFPG 350
FVSWRDPKSG SWYVETLDDI FEQWAHSEDL QSLLLRVANA VSVKGIYKQM 400
PGCFNFLRKK LFFKTS

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