Tag | Content |
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EnhancerAtlas ID | HS190-00110 |
Organism | Homo sapiens |
Tissue/cell | Treg_cell |
Coordinate | chr1:12231160-12236080 |
TF binding sites/motifs | TF | JASPAR ID | Coordinate | Motif Sequence | Strand | -Log10(p-value) |
CREB3 | MA0638.1 | chr1:12235443-12235457 | CTGCCACGTCACCC | + | 6.73 | FOXP1 | MA0481.2 | chr1:12233024-12233036 | TTCTGTTTACTT | - | 7.22 | FOXP2 | MA0593.1 | chr1:12233025-12233036 | TCTGTTTACTT | - | 6.32 | GATA2 | MA0036.3 | chr1:12232427-12232438 | TTCTTATCTGT | + | 6.14 | Gata1 | MA0035.3 | chr1:12232427-12232438 | TTCTTATCTGT | + | 6.62 | Nr5a2 | MA0505.1 | chr1:12231941-12231956 | TCTGACCTTGACCTT | - | 6.94 | REST | MA0138.2 | chr1:12235219-12235240 | TTCAGGAGCAAGGCCAGAGGC | + | 6.06 | RORA | MA0071.1 | chr1:12231949-12231959 | TGACCTTGAT | - | 6.02 | SP1 | MA0079.4 | chr1:12235246-12235261 | AGTGGGCGGGGCCTG | - | 6.76 | SP2 | MA0516.2 | chr1:12235245-12235262 | GAGTGGGCGGGGCCTGG | - | 6.64 | SP4 | MA0685.1 | chr1:12235244-12235261 | GGAGTGGGCGGGGCCTG | - | 7.2 | Stat4 | MA0518.1 | chr1:12233725-12233739 | CGTTTTCCTGGAAG | - | 6.23 | ZNF263 | MA0528.1 | chr1:12231491-12231512 | TCTCCTTCCCTCGCTTCCTTC | - | 6.08 | ZNF263 | MA0528.1 | chr1:12234302-12234323 | TTCTCCTTCTCCTTCTTCTTC | - | 6.47 | ZNF263 | MA0528.1 | chr1:12234206-12234227 | TTCTTCTTCTTCTTCTCCTTC | - | 6.52 | ZNF263 | MA0528.1 | chr1:12234209-12234230 | TTCTTCTTCTTCTCCTTCTCC | - | 6.7 | ZNF263 | MA0528.1 | chr1:12234212-12234233 | TTCTTCTTCTCCTTCTCCTTC | - | 7.12 | ZNF263 | MA0528.1 | chr1:12234215-12234236 | TTCTTCTCCTTCTCCTTCTCC | - | 7.13 | ZNF263 | MA0528.1 | chr1:12234299-12234320 | TCCTTCTCCTTCTCCTTCTTC | - | 7.15 | ZNF263 | MA0528.1 | chr1:12234221-12234242 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234227-12234248 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234233-12234254 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234239-12234260 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234245-12234266 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234251-12234272 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234257-12234278 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234263-12234284 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234269-12234290 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234275-12234296 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234281-12234302 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234287-12234308 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234293-12234314 | TCCTTCTCCTTCTCCTTCTCC | - | 7.65 | ZNF263 | MA0528.1 | chr1:12234218-12234239 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234224-12234245 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234230-12234251 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234236-12234257 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234242-12234263 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234248-12234269 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234254-12234275 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234260-12234281 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234266-12234287 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234272-12234293 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234278-12234299 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234284-12234305 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234290-12234311 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 | ZNF263 | MA0528.1 | chr1:12234296-12234317 | TTCTCCTTCTCCTTCTCCTTC | - | 7.89 |
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| Number of super-enhancer constituents: 43 | ID | Coordinate | Tissue/cell |
SE_00369 | chr1:12226565-12247198 | Adipose_Nuclei | SE_01471 | chr1:12232095-12234188 | Adrenal_Gland | SE_01471 | chr1:12234592-12236046 | Adrenal_Gland | SE_04546 | chr1:12232368-12233932 | Brain_Anterior_Caudate | SE_04546 | chr1:12234570-12236102 | Brain_Anterior_Caudate | SE_06521 | chr1:12231395-12234253 | Brain_Hippocampus_Middle | SE_06521 | chr1:12234379-12243644 | Brain_Hippocampus_Middle | SE_09154 | chr1:12224797-12249846 | CD14 | SE_10696 | chr1:12231624-12233979 | CD19_Primary | SE_11902 | chr1:12231048-12236114 | CD3 | SE_14553 | chr1:12231008-12236205 | CD4_Memory_Primary_7pool | SE_15480 | chr1:12231304-12235464 | CD4_Memory_Primary_8pool | SE_16369 | chr1:12231214-12235920 | CD4_Naive_Primary_8pool | SE_16946 | chr1:12231228-12235850 | CD4p_CD225int_CD127p_Tmem | SE_17650 | chr1:12231292-12241643 | CD4p_CD25-_CD45RAp_Naive | SE_17827 | chr1:12231021-12246713 | CD4p_CD25-_CD45ROp_Memory | SE_18389 | chr1:12226183-12250288 | CD4p_CD25-_Il17-_PMAstim_Th | SE_19117 | chr1:12225970-12243644 | CD4p_CD25-_Il17p_PMAstim_Th17 | SE_20048 | chr1:12231058-12236137 | CD56 | SE_20873 | chr1:12231198-12236438 | CD8_Memory_7pool | SE_22347 | chr1:12226250-12242299 | CD8_primiary | SE_26251 | chr1:12232165-12234254 | Duodenum_Smooth_Muscle | SE_26251 | chr1:12234361-12236001 | Duodenum_Smooth_Muscle | SE_27503 | chr1:12231615-12234368 | Esophagus | SE_27503 | chr1:12234497-12236079 | Esophagus | SE_30788 | chr1:12232018-12234343 | Fetal_Muscle | SE_30788 | chr1:12234469-12236114 | Fetal_Muscle | SE_32030 | chr1:12231844-12234207 | Gastric | SE_32030 | chr1:12234507-12236040 | Gastric | SE_38661 | chr1:12234401-12236100 | HUVEC | SE_41498 | chr1:12232230-12236136 | Left_Ventricle | SE_42336 | chr1:12231389-12236106 | Lung | SE_48967 | chr1:12232188-12234263 | Right_Atrium | SE_48967 | chr1:12234520-12236102 | Right_Atrium | SE_50250 | chr1:12231283-12234299 | Sigmoid_Colon | SE_50250 | chr1:12234498-12236097 | Sigmoid_Colon | SE_52522 | chr1:12231293-12236092 | Small_Intestine | SE_53313 | chr1:12231250-12236109 | Spleen | SE_55394 | chr1:12232096-12233341 | Thymus | SE_55394 | chr1:12233345-12234247 | Thymus | SE_55394 | chr1:12234547-12235437 | Thymus | SE_55394 | chr1:12235467-12236045 | Thymus | SE_61096 | chr1:12184746-12245090 | HBL1 |
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| Diseases: AD,Huntington,Obesity,Parkinson,Prostate cancer,Schizophrenia and Sleep disorder | Number of disease enhancers: 8 | Chromosome | Start | End |
chr1 | 12232096 | 12232448 | chr1 | 12233600 | 12234159 | chr1 | 12234600 | 12236012 | chr1 | 12235070 | 12235463 | chr1 | 12231693 | 12231881 | chr1 | 12233531 | 12233800 | chr1 | 12233800 | 12234000 | chr1 | 12234000 | 12234197 |
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Enhancer Sequence | GCAATTTTCC CACCTCAGCC TCCCAAGTAG CTGGGATTAC AGGTGTGTGC CACCATGCCC 60 GGCTAATTTT TCCTTTTTTT TTTTTTTTTT AGTAGAGACC GGGTTTTGCC ATGTTGGCCA 120 GGCTGGTCTC GAACTCCTGA ACTCAAGTGA TCCACCTGCC TCGGCCTCCC GAAGTGCTGG 180 GATTATAGGC GTGAGCCACC CCACCCAGCC CCATTCTCAC TTTTAAGCCA TGCTTTTCTG 240 TCCTCAGATG TGCTGCACAC ACACCTGCTC CAGGGCCTTT GCACTTGCTT TCCCCATCAC 300 CTCCAATACT CCTCCTGCTG ACGTCTCTTG GTCTCCTTCC CTCGCTTCCT TCTGCTGAAG 360 TAGACAATCC TGCCTGTAGG TGCTCCCTGC CAGGCACTCT CACTCCCTGA CCTGCTTTGT 420 ATTCCTGTAT AATGCTCTTG ACCTATTCTA TTTATTTCAC TTTTATTATG TCTTCCCACA 480 AGATTGTAAG TACCGTGAGG ACAGGGACTC ATTCACCACT GTAGACTCTA GCCTAGAAGA 540 GGGTTTTTCA GTCAGTGCCT CTGACTTTAA TTCTTTGTTG TGGGGCTGTC CCGTGAGCTG 600 TAGGATGTTT AGCGACATCC CTGGCCTCTA CTTATTGGAT GGCAGTAGCG CCACCCTCCC 660 TCGTGACAAA AATATCTCCA GATATTGCTA AGTGTCCTTT GGGGTTGGGG GATTGCCCCT 720 GATTGAGAAC CACTGGCCTA GGACAGTGCC TGGCACATAG TAAGTGTTCA AAAAATATTC 780 ATCTGACCTT GACCTTGATA ATGGCCCTGT TTTACAGATG AGACGGGGGT TTGAAAAGTC 840 AGTGGTGGCA GGGTGGGGTT CTGTTTGCCT CCATCTCTTG GGGTATTTTT CTGGGCTCCT 900 CTTCCCATTG AGTGGTGTCT GCTGAGGTTA GGGGTCCTCT CCCCAAATTG CTCACCCCCT 960 CGACATCCCT CGTGTAGTGA GGGATGGGGC CACTCACTGA CGGTGACTCA GGGCCCCAGA 1020 ATGCATGTGA TTTACCCAGA AGCGGGCAAG GAGGGAAGCT GGGGTTTGGG GTGCCGGGGA 1080 TGAACAGGAA CAAAGGAGAG GCGCTGTGGC TCCCCGTTCT GGACCCTCGT CTGGCCACAG 1140 GGAAGCAGCA CTGATGACTC TGGGGAAAGG CCCCGGCCTC TGAATCAGAT AAACCTCAAG 1200 TCGCTGCTCT GCTGTTTTAC TGGCTGTGTG ACCTGGGCAA GTCTTTCTAT CCCTCGGAGC 1260 CTCTGTGTTC TTATCTGTAA AATGGGAGTA ATCCTAGCCT CACGGGCTGG CTGTCAGGAT 1320 TAAAAGTGCT TTCTAATCCT GGCATTGGCA GCTATTTGAG CCATTGGTGG CTTTGCAGGT 1380 CTGACCCGAC TCTCTGGGCC ATGGGGTGGT GCTCGGGCCT AGGTGGGGAC CCCTGTGGAG 1440 TCAGACTGTC TGCTCTGAGC CCCAGGGCCC TGAAGCTTGG GTGGCAGCCC TGCAGTTGCC 1500 CAGAGTTCCT GTCTAAGTGG CTTTGTTGCC CATCATCTCA GAAAGCAACT TCTTTCCTCC 1560 CTGCCTTTTC CTGTCTGTGC TTCTGCCCCA GTGCCCCCTG GCTGGGCTCT CAAACCCACT 1620 GCTTGACAGC CTGGTCTTAG GACACTGTAT TGTGGCAAAG GCTGTGGGGT CAGGATATCC 1680 CCTCCCCTCC CTTTGCCACC CCTTTTAGTG AGTAACAGGT GCTGTGTGTT TTGGGGATGA 1740 GTGAAGGGTA CATTTGGTGA AGCACAGAGA GAGTGCACAA GGCTTCAGTT TGCAAGATGG 1800 GCACGGGAAG ATTCCAGGCC ATCTCCAAAA CCTCTTCCAT CTCCAACCTC TGTGCTGCTG 1860 AAGGTTCTGT TTACTTGTGA CCCTGAGAAG GGGATGCCCT ATGGGGGCTC TTCTGAGATC 1920 ATGCTGTCCA TTTTCCTGCC TCCAAGTGAC TTCTAAGACA GCATGGCTCT GAGGAAGGAG 1980 CACTGACTTG GGTGTTGGGA GATCACAGTT CCCATCTGAG CACCGTCACT GGCTTGCTGT 2040 GCTACCTTGC TTGGGTTACT TAACCTCTCT GGGCCTAAGC ATCCCTATCT ATGAAACCTA 2100 ACAACCCTGG TTCCAATGCT TTCCTAGAAT ATTGGGGAAG TGTCGGCTTT GAGTATACTT 2160 GACAAAGGCC ACAGATTGGG GGTGGGGTAT ATAAAAGTCT ACAGGAAGGA GAGCCCAGGA 2220 CTCCCCACTG TCAATATCTT GGTTCCCCAG CTTCTCTTCT TCTTGCTGAC CTCAATCTCA 2280 CTTGCTTTGG GTGGATTGAT TTCCTGACTC AGGCTCCAGG GCCATCAAGA ATTCACGGCT 2340 GCCTTTCAGC CTTCATGAAG GACATGGTGG AGCTCCTTAG GCAGAACTGG GGTTTGTGGA 2400 TGTCCTGCCT CTCTGCCCCT TGGTACCTAG GTGGCACCTT TTCAAGTTCG GGAGCTAGAT 2460 CCTTTCCCCT TCCCCACACT GTAGGAAAGT CCTTACTGTA GGCAGGCGCT GCAGAGCCTG 2520 CTGTCTGGGA ACCCACAGGT TCAAGGAAGC CTTGAGCAGG AAGGGCGTTT TCCTGGAAGA 2580 AGCCCTTTGT CGCTGGTAAT GGGTGCAGGC TGCTCTGACC CGGTTCTGAG TCCTGCCCCC 2640 TTCCAGGCCT AGGGCTTTGG GCCTTGATCA CCTCTGCTGA GTAGCTGACT GCGGGGCTGG 2700 GGCTCTGATG CTCAGGACCC ACCTCTCTGG GACCCACAGT CTTTTTCCAC TGTGGCGTGT 2760 AGTGATGTCA CAGGTGGCAG TGATGTCACT GTGGTTTGAG GTACTTGGCT GTGAGCCCCG 2820 GAGGAGGAAG TGTCTGTTCG CTGATGGGGG GTTGGAAGAG ATCATTGACT TCTGCCCCAA 2880 GCGTGAGCCC CAAGTGTGCA GGGGGGAGTG CGGGGGGAGG GCTGTTGGCG GCGCATCCCA 2940 GGGCTCTGGC TCTGCCCTTG CATCTAGCCT GTCTTTCCTG TGGGCTGTGA CAAGCCACTC 3000 TGCATCTCTG AGACTCCATT TCTTCTTCTT CTTCTTCTTC TTCTTCTTCT TCTTCTTCTT 3060 CTCCTTCTCC TTCTCCTTCT CCTTCTCCTT CTCCTTCTCC TTCTCCTTCT CCTTCTCCTT 3120 CTCCTTCTCC TTCTCCTTCT CCTTCTCCTT CTCCTTCTTC TTCTGATGGA GTCTGACTCC 3180 GTTGCCCAGG CTGGAGTGCA GTGGCGTGAT CTTGGCTCAC TGCAACCTCT GCCTCCCAGG 3240 TTCAAGCTAT TCTCCAGCCT CAACCTTCCA AGTAACTGGG ATTACAGGCA TGCACCACCA 3300 CACCCGGCTA GTTTTTGTAT TTTTAGTAGA GATGGGGTTT CACCATGTTG GCCAGGCTGG 3360 TCTCGAACTC CTGACCTCAA GTGATCTGCC CGCCTTGGCC TCCCAAAGTG CTGGAATTAC 3420 AGGCGTGAGC CACTGCGCCC AGCTTCCATT TCTTCTTTGA AAAGTAGGAG GGGTTGGAAT 3480 TGTCACCCTG GAGGTTCATG GTTGCTAGAT TATTGATTCT GTTGCTGGAT TCAGGAGACC 3540 TGTTAGCTGG CTAGTTCACA GCAAGTATTG GGTGTTTGGA GGGGGGCTGC AGAGCCCCTT 3600 CTCAGGCCCC AGGAGGGCCA GCTGCCCTCC CTACCCCCTC TTTTGGACAC TAGTGGGCAT 3660 GTTCTGCTGG GAAAACAGAC AGTGTAACCT GACTTCGAGG GCTGCAGGCT GAATCTCTTT 3720 CAGATGTACT GGCTCCTTGA GAGGCCTAGC AGATCTCTAC TCTGTGGGTC CCTTTCGGAG 3780 CTGGGGCTCA GGTTTGACCC AGCCACTCTG ACCGGAGACA GCGCAGAAAT CACCAGGAGC 3840 ATTTGTTTGT TTTCCTTTGC TGTCCAGACA GTGGCCCACC GTCTGCTTCA GTCTGAGCGT 3900 GGCCCTGCAC TAGTGAGACT GATGTGGCCA CAGGTTCAGA GAATCAGTGC GCCTGAGTGG 3960 GAGAGCAGAG CGGGAGGGGA TTTGGAGGCA GGCGGGCTGT GGACAGGGAG GGGGGAGGAC 4020 ATCTTCCGAG CTGTCAGCGG GAGGCCTTCT TGAAGGTCTT TCAGGAGCAA GGCCAGAGGC 4080 CGTGGGAGTG GGCGGGGCCT GGGGCTGGGA GTCAGGGGTC TGAGGCCTCA TCTTGGCCCG 4140 GCCTCTGCTT CCGGGAGAAC TTGGCCAATT CCCTTCTCCT TTCTGAACCT TGGTGGCCCC 4200 AGCTGTCACT TGAGATTAGC AAGGACCTCC CTGGTCCCAG CAGGAGTGAG TGGCTTTGGG 4260 CAGGGGGTGG AGTGCAGATT GCACTGCCAC GTCACCCAGC TCAGAAGGCC CAGGTGTGGT 4320 CCAGCTGTGG ACTTGATTGT GAACTCCTGG GGAAGGGCTC TGGTCCTTTG CCTCAGTTAG 4380 CGGGACCCCC ACCAGTGCCC TGGGTGCCCC TGCTGGCCCC TCCTCTCGCT GACCCCAGCC 4440 CCAGTTTCTG GCTGCAACTC ACAGAGGCCC CAGGCTCCTG TGGCCCCATC ACCAGCAGCT 4500 CCTGCTGTCA TTTCCTGAGC CTCGCAAGCC CCTAATCCTG CTCCTTCCTG TCCTGGCCCC 4560 CAGCTCCCTC AAGCCCCACT CCTGCATCCC ATTCTCCCTG GACATCACCC CTCCCACCCC 4620 TTGGCTCAAT TTCCTTCCTG TCGTGGCTTG GTCCTTTGGT CATTGCCCTG GTCTTTTCTT 4680 GTCCCCTTCC TGATTCTGCC CTTCTCCAGG CCCACACGGG GAACCTCCTA ACCGCTGAGC 4740 CCTGAAAGGT AGGCGGGTTT AGGATGAGTG GCTACAGGGA GGAGAATGGT GTGGGGAGAG 4800 AGATATGGAG GAAAGAATAT TAGGGGACAG GCCGGGCACG GTGGCTCACG CCTGTAATCC 4860 CAGCACTTTG GGAGGCCAAG GCGGGCGGAT CACTTGAGGT CAGGAGTTGG AGACCACCCT 4920
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